July 2009

A New Solution for Endotoxin Removal in Biomanufacturing Processes

EndoTrap HD® manufactured by Hyglos GmbH (former Profos AG) is a new revolutionary tool especially designed to meet the needs of pharma and biotech industry for the efficient removal of endotoxins in biomanufacturing processes. EndoTrap® HD fulfils all requirements for industrial applications, and it can easily be integrated in/at early or late-stage purification processes of biological substances such as proteins, drugs, antibodies, or vaccines. Background Endotoxins (lipopolysaccharides, LPS) are major contaminants found in commercially available proteins or biologically active substances.…

Viresolve® Pro and Pro+ Solutions: Next-Generation Parvovirus Safety

Figure 1: Millipore Corporation’s new Viresolve Pro and Pro+ solutions are a major leap forward in virus clearance technology. As biotech manufacturers experience high titers, the evolution of process platforms and increasing focus on cost of goods, the demand for a robust high-capacity unit operation is increasing. Viresolve Pro and Pro+ solutions deliver robust parvovirus clearance, high productivity, and performance assurance. The Viresolve Pro and Pro+ solutions offer the highest level of virus clearance for the development of biopharmaceutical products.…