Author Archives: Ray Ismail

Production of T Cells for Adoptive Cellular Immunotherapy: Using the Xuri™ Cell Expansion System W5

The Xuri cell expansion systems (Xuri W25 and W5) provide a functionally closed, single-use bioreactor that requires fewer operator intervention steps, reduces the risk of contamination, and controls the cellular environment to maximize cell yield. Data presented here highlight that at a cellular level, results from different bioreactors may appear similar, but differences can exist at the receptor expression level. Expansion of T Cells Peripheral blood mononuclear cells (PBMCs) were expanded in static culture. On Day 5, 2-L Xuri Cellbag…