Author Archives: Lars Stöckl

Production of Biotherapeutics Using GlycoExpress® Expression Platform Technology

GlycoExpress® (GEX®) technology is a well-established human expression platform for the screening and production of biotherapeutics. By contrast with other human cell lines (e.g., HEK293 and Per.C6) GlycoExpress® expression platform consists of a toolbox of glycoengineered cell lines optimized for producing biotherapeutics with desired glycan structures to improve their clinical performance. Glycotope’s GEX® technology provides an established expression platform proven for different biopharmaceuticals: Antibodies of different isotypes (e.g., IgG, IgM, IgA) Defucosylated antibodies Bispecific antibodies/fragments (e.g., NK cell/T-cell recruiters) Difficult-to-express…