Enzo Life Sciences, Inc APP ΔC31 ELISA Kit from Enzo Life Sciences, Inc. for the Quantification of a Novel APP Cleavage Fragment Associated with Alzheimer’s Disease Further establishing its position as an innovator in tools for detection of neurodegenerative diseases, Enzo offers a high sensitivity APP ΔC31 ELISA Kit; a one-of-a-kind quantitative ELISA for Alzheimer’s research . Unlike the more familiar β-amyloid and tau fibrillar pathway leading to amyloid plaques and tangles, APP ΔC31 reveals an alternative, unique pro-apoptotic mechanism…
Author Archives: BPI Contributor
NeoStem Expands Treg International Patent Portfolio with Granting of Patent in Japan
NeoStem, Inc. New York, February 4, 2014 – NeoStem, Inc. (NASDAQ:NBS) (“NeoStem” or the “Company”), a leader in the emerging cellular therapy industry, today announced the expansion of intellectual property protection surrounding the Company’s T-regulatory cell (“Treg”) program with the grant of Japanese Patent Number 5409827 titled “Methods for the Isolation and Expansion of Cord Blood Derived T Regulatory Cells.” This grant further expands the scope and reach of NeoStem’s Treg patent estate internationally. Through its Treg program, NeoStem is…
Recommendations for Extractables and Leachables Testing
This podcast features: Raymond Colton
A versatile high capacity, single-use chromatography tool with superior salt tolerance, process robustness and impurity removal
Strong anion exchange (Q) chromatography has become an industry standard in the polish purification steps of mAb production. It is a proven technology to remove DNA, viruses, endotoxins and acidic host cell proteins from process feed streams in flowthrough mode. As the industry pursues an increasing interest in downstream single-use technologies and flexible biomanufacturing due to advancements in cell culture technology and the emergence of cost-sensitive biosimilars, conventional purification technologies present limitations. Despite their high binding capacity, traditional resin-based chromatography…
February 2014 Issue Author Insights
Sartorius appoints internationally experienced laboratory manager to join its top management team
Sartorius Michael Melingo to succeed Dominique Baly in the Sartorius lab business Goettingen, January 30, 2014 – Effective April 1, 2014, Michael Melingo will head marketing, sales and services of the Lab Products & Services Division at Sartorius. He will therefore succeed Dominique Baly, who will retire from the company as planned after reaching retirement age. Michael Melingo will report to CEO and Executive Board Chairman Dr. Joachim Kreuzburg and be a member of the Group Executive Committee, the highest…
EMD Millipore Expands its EMPROVE Raw Materials Portfolio to 400 Products
EMD Millipore • Portfolio now includes 400 active pharmaceutical ingredients, excipients and biopharmaceutical materials • Application-specific documentation streamlines pharmaceutical process and reduces qualification costs • Increases patient safety by avoiding errors inherent in manual documentation Billerica, MA – EMD Millipore, the Life Science division of Merck KGaA of Darmstadt, Germany, today announced the expansion of its EMPROVE® raw materials portfolio to 400 active pharmaceutical ingredients, excipients and biopharmaceutical materials. The products offer comprehensive application-specific documentation in addition to superior quality,…
Quattroflow to Highlight Single-Use Benefits of Quaternary Diaphragm Pumps at INTERPHEX 2014
Quattroflow, part of Pump Solutions Group Quattroflowâ„¢ to Highlight Single-Use Benefits of Quaternary Diaphragm Pumps at INTERPHEX 2014 Kamp-Lintfort, Germany, January 22, 2014 — Quattroflowâ„¢, part of Pump Solutions Group (PSG®) and a leading brand of positive displacement quaternary diaphragm pumps for the biopharmaceutical industry, has announced that it will display the latest offerings in its line of pumps for use in pharmaceutical and biologic-handling applications at INTERPHEX 2014 in Booth No. 2633. The INTERPHEX Show, which brings together a…
KDG Acquires Marcor to Enter Bio and Nutraceuticals Market
KODA Distribution Group Marcor Development Corp., a New Jersey-based distributor for more than 35 years of specialty chemicals and naturally derived ingredients for use in nutraceuticals, biologicals, pharmaceuticals and related applications, announced that it is being acquired by KODA Distribution Group (KDG), the leading US specialty chemical distributor. Marcor will maintain its current management and staff, operating from its Carlstadt, NJ headquarters. Charles Garbarini, President, noted “we welcome the opportunity to be the foundation of KDG’s growth into these markets…
Electrophoresis: Analysis By Size and Charge
BPI Lab An essential method in modern analytical laboratories, electrophoresis separates macromolecules (DNA, RNA, and proteins) for analysis based on their size and charge. The popular sodium-dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) technique uses a gel medium. Capillary electrophoresis (CE) can separate ionic species by charge and hydrodynamic radii as well as frictional forces in small electrolyte-filled capillaries. Cheryl Scott looks at the history and applications of these techniques, highlights their appearance in past BPI articles, and points to some…