EMD Millipore, the life science division of Merck KGaA of Darmstadt, Germany, has expanded its single-use film offerings with the introduction of PureFlexâ„¢ Plus film, a robust, durable film used in the construction of Mobius® single-use process containers for biopharmaceutical manufacturing. The film’s rugged outer layer offers strong resistance to leak formation, making it ideal for the demanding applications often encountered in large volume operations. The PureFlexâ„¢ Plus film builds upon EMD Millipore’s established PureFlexâ„¢ film technology, which was introduced…
Author Archives: BPI Contributor
EMD Millipore Introduces New Processing Technologies in Booth 517 at the BioProcess International Conference & Exhibition
EMD Millipore, the Life Science division of Merck KGaAÂ of Darmstadt, Germany, invites you to visit booth 517 at the BioProcess International Conference & Exhibition October 20-23 in Boston to learn about its new biopharmaceutical processing solutions. These products add to EMD Millipore’s complete range of upstream and downstream products, helping to improve manufacturing productivity and accelerate time to market. The new technologies on display at the BioProcess International Conference & Exhibition will include: PureFlexâ„¢ Plus Single-Use Process Container Film EMD…
CaPure-HA Resin for Aggregate Removal from Monoclonal Antibodies
Scientists in the field of process chromatography methods development are constantly on the lookout for better and more selective ways to remove aggregates and other process related impurities from monoclonal antibody monomer. The data presented in the following paper demonstrates the capabilities of CaPure-HA to remove degradation products, dimer, and higher order aggregates from the monomer of a protein A purified IgG1 monoclonal antibody.
Promethera Biosciences Receives Approval in Belgium to Enroll Patients in the Imminent HEP002 Phase 2b/3 Clinical Trial
Promethera Biosciences, a Belgian biotechnology company developing Promethera® HepaStem, a cell-based therapy for the treatment of both orphan liver-based metabolic diseases and acquired liver diseases, today announces that Belgium has authorized the conduct of a trial designed to treat paediatric patients with urea cycle disorders (UCD) in a Phase IIb/III study (HEP002). This first agreement officially opens the start of the second clinical trial conducted by the company. Belgian patients will be recruited and treated in Cliniques Universitaires Saint-Luc in…
Multitron Pro: The Professional Incubation Shaker for Any Application
The Multitron Pro and the Multitron Cell manage to combine flexibility, user-friendliness and operational reliability with  optimum space utilization. A number of innovative options for cooling, precise CO2 control, illumination and hygienic direct steam humidification guarantee the ideal conditions for cultures. With around 500 different designs we meet almost every customer requirement. We are also more than happy to provide special configurations. INFORS HT provides you with Swiss quality with a modern design and a high technological level and environmentally friendly energy…
Increase Protein Yield through Optimization of Suspension CHO Transient Transfection
This webcast features: Laura Juckem, PhD, R&D Group Leader, Mirus Bio High efficiency transient transfections of suspension CHO cells enable researchers to bridge upstream and downstream processes and provide confidence that recombinant protein will have the same properties throughout the drug discovery pipeline. To address this need, Mirus Bio has developed the TransIT-PRO® Transfection Kit to maximize plasmid DNA delivery and therefore recombinant protein yield. There are several important parameters to consider during transient transfection including: (1) growth media compatibility,…
Biotechflow EBA MAb Purification from Unclarified Harvest PC
Scalable Protein Production Using Flow Electroporation
Many transient gene expression (TGE) methods produce insufficient protein quantities for full use within biotherapeutic and vaccine development pipelines. MaxCyte’s proprietary flow electroporation provides a universal means of highly efficient TGE for the rapid production of large-scale quantities of proteins, antibodies, antibody-like molecules, virus-like particles (VLPs), and vaccines. In addition, the platform can be used for generation of stable pools and stable cell lines that can greatly streamline biotherapeutic and vaccine development. Flow electroporation (co)transfects a wide range of cells,…
Security of Supply for Chromatography Media
This white paper discusses GE Healthcare Life Sciences extensive preventive actions taken to help secure a continuous supply of chromatography media for biopharmaceutical manufacturers.
Regulatory Compliance in Single-Use BioManufacturing Facilities Requires a Collaborative Approach with your Supply Chain
This podcast features: Todd Kapp, Market Development Manager, Parker domnick hunter This podcast was recorded based on the presentation given at the 2014 BioProcess Theater which took place at the 2014 BIO International Convention, June 23-26, 2014. The BioProcess Theater, a 50-seat amphitheater located on the exhibition floor at the heart of the BioProcess Zone, provided attendees with daily, complimentary opportunities to listen, learn, and interact with leading experts as they presented, discussed and debated the latest business and scientific trends impacting…