The list of winners of the prestigious CASSS Award for Outstanding Achievements in Separation Science reads like a who’s who of the field. But beyond the award, the details of the winners’ contributions to separation science are being lost to time. No information about the early recipients can be unearthed, and only a short career summary for the seven newest winners has been available on the CASSS website. As time passes, the lives and stories of these winners would likely…
Author Archives: BPI Contributor
Dr. Cari Sänger-van de Griend Named 2015 CE Pharm Award Winner
CASSS recently announced Cari Sänger-van de Griend, PhD, as the 2015 winner of its CE Pharm Award. The CE Pharm Award recognizes an individual for sustained and significant contribution to the practical application of capillary electrophoresis (CE) to the analysis of biotechnology and pharmaceutical products. It is awarded at the CASSS CE Pharm meeting. CE Pharm provides an interactive forum for the discussion of CE in the pharmaceutical and biotechnology industries, including regulatory considerations. The forum also provides a venue…
Scientists Honored for Important Research on Mass Spectrometry
William Gilliland Jr. and Nalaka Rannulu recently received the Best Poster Awards at the 2015 CASSS Mass Spec Symposium. Gilliland won with a poster on “Microchip Capillary Eletrophoresis Coupled With High Pressure Mass Spectrometry for the Analysis of Amino Acids and Other Metabolites.†He is a research assistant at the University of North Carolina, Chapel Hill. “This work focused on the application of this novel combination of technologies to measure analytes in cell growth media with high resolution and specificity…
Robust, Load Independent Viral Clearance in Monoclonal Antibody Purification
Anion exchange chromatography is an important flow-through polishing step for viral clearance of monoclonal antibodies. Resin based materials are most commonly used for this but the large size of virus particles limits diffusion and binding capacity. It is therefore necessary to use large volumes of resin and oversized column hardware. Column chromatography as a unit operation also means high operational costs, including validation, cleaning and storage. This is a particular issue for clinical manufacturing, where a column is used for…
Sartorius Stedim Biotech Presents SARTOFLOW® Smart Crossflow Filtration System for Process Development
Sartorius Stedim Biotech (SSB), an international leading supplier for the biopharmaceutical industry, announces the launch of SARTOFLOW® Smart, the smart and easy benchtop crossflow system for optimized ultra- and diafiltration applications. It can ideally be used in many downstream processes, such as purification of vaccines, monoclonal antibodies and recombinant proteins. The system is suitable for flexible use in laboratory environments for process development and clinical trials as well as for cGMP environments. The brand new system is equipped with a…
Lonza Expands Single-Use Manufacturing Capacity in Slough Facility to Meet Customer Demand
Lonza, a global leader in biological manufacturing, today announced the expansion of mammalian production capacity at its Slough (UK) facility. Based on the increased demand for biopharmaceutical development and clinical manufacturing services, two 1000L single-use bioreactors will be installed at the site. This expansion will significantly increase the existing single-use manufacturing capacity in Slough while allowing current operations to continue without interruption. The additional mammalian manufacturing capacity is now available to customers. Lonza’s cGMP facility in Slough is the center…
MilliporeSigma Donates to American Red Cross to Support Greater St. Louis Flood Victims
MilliporeSigma, the U.S. life science business of Merck KGaA, Darmstadt, Germany, today announced it has donated $10,000 to the American Red Cross of the Greater St. Louis Region in support of the organization’s flood relief efforts. In addition, the company will match any Red Cross donations made by its employees in St. Louis and St. Charles, Missouri. “Our company has a long history of giving back to the communities in which we live and work,†said Udit Batra, president and…
New Swabbable Needleless Injection Sites with T-Ports from Qosina
Qosina is pleased to announce the addition of three new t-port swabbable needleless injection sites, in stock and ready for immediate delivery. The ports are available to fit 0.079 inch OD tubing (2 mm) (#80172), 0.122 inch OD (3.1 mm) (#80174) or 0.157 inch OD tubing (4 mm) (#80171) and feature a swabbable luer activated female luer lock for aspiration or injection. The t-ports are designed to be bonded in-line and the valve offers high flow rates. Made of a…
Single-Use Biopharma Product Recycling: An Alternative Process to Unlock the Challenges
This webcast features: Jacqueline Hollands Ignacio, Corporate Responsibility Programs Manager – Customer Initiatives, MilliporeSigma, and Michael Farrell is Corporate Disposal Coordinator, Triumvirate Environmental. As the biopharmaceutical industry increases the adoption of single-use manufacturing products, the issue of recycling becomes a challenge. Disposal and recycling the plastics from these products is a challenging task due to many factors such as limitations within the recycling infrastructure, products containing a mix of materials and plastics, and biopharmaceutical products can contain biologically hazardous materials…
Development and Optimization of CHOgro® Transient Expression Technologies for High Titer Antibody Production in Suspension CHO Cells
During early stage drug development, quickly obtaining relevant candidate proteins through transient transfection can accelerate drug discovery. High titers are often obtained from Human Embryonic Kidney (HEK) 293 derived cell types; however, the use of different host cells between early stage transient and later stable protein production is a concern and can lead to the advancement of false-positive candidates. Chinese hamster ovary (CHO) cells are a desirable target cell type due to growth characteristics and a history of regulatory approval;…