MilliporeSigma’s Mobius® Power MIX 2000 single-use mixing system is engineered with advanced technology to effectively handle difficult-to-mix buffers, culture media powders and other pharmaceutical ingredients. The Mobius® Power MIX achieves a strong vortex using an impeller design and motor based on magnetically-coupled NovAseptic® technology, a proven mixing technology in stainless steel tanks. The Power MIX 2000 provides accessible, sterile zero deadleg sampling directly from the mixing container. A Probe Port allows for insertion of either a reusable probe for non-aseptic processes or a…
Author Archives: BPI Contributor
Top 5 Considerations When Looking to Outsource to a Biomanufacturing Partner
This webcast features: Paul Jorjorian, Director, Global Technology Transfer, Patheon Biopharmaceutical companies are facing increasing constraints when developing and manufacturing their large molecule drugs. Development labs and manufacturing suites have limited capacity making it nearly impossible to right size internally for uncertain forecasts. As a result, selection of the right biomanufacturing partner has never been more important – for small and mid-size biopharma companies alike. There are an ever-increasing number of options and many criteria to consider during the vendor…
Bio-Rad Launches Nuviaâ„¢ IMAC Affinity Resin for Process Scale Purifications at Bioprocess International Conference and Exhibition 2016
Bio-Rad Laboratories, Inc. (NYSE: BIO and BIOb) released Nuviaâ„¢ IMAC Resin, an immobilized metal affinity chromatography resin optimized for use from lab scale through pilot studies to process-scale manufacturing, at the 2016 Bioprocess International Conference and Exhibition, Boston, Oct. 4–7. Bio-Rad (Booth #1129) will also exhibit a host of customizable workflows designed to simplify and speed up drug discovery and development, including automated multicolumn protein purification, host cell protein and host cell DNA analysis, and CRISPR/Cas9 transfection and monitoring. A…
Biologics candidate manufactured using Ajinomoto Co., Inc.’s CORYNEX® Protein Expression System enters clinical trials for the first time
Ajinomoto Althea, Inc. (“Altheaâ€) announced that a biologics candidate developed by a Japanese global pharmaceutical company and manufactured at Ajinomoto Althea using CORYNEX® Protein Expression System, has entered phase I clinical trials. The CORYNEX® system of Ajinomoto Co., Inc. (“Ajinomoto Co.â€) is a proprietary protein expression platform that combines the best attributes of mammalian and microbial systems. It greatly simplifies the processes to produce and purify recombinant proteins resulting in reduced production costs and greatly speed time to market. The…
Tosoh Bioscience Introduces TOYOPEARL® Sulfate-650F Process Chromatography Resin
Tosoh Bioscience LLC, a provider of chromatographic resins for the purification of biopharmaceutical drugs in commercial manufacturing processes, today announced the introduction of TOYOPEARL Sulfate-650F, a strong cation exchange resin that exhibits high salt tolerance. TOYOPEARL Sulfate-650F resin is now available for sale in the Americas from Tosoh Bioscience LLC. TOYOPEARL Sulfate-650F resin allows for lowered operating costs by offering higher dynamic binding capacities for IgG. This resin can easily achieve a dynamic binding capacity of >120 g/L of monoclonal…
Thermo Fisher Scientific Expands Global Footprint to Support Cell and Gene Therapy Clinical Trials in Japan
To help meet increasing demand for cell and gene therapy clinical trial support around the globe, Thermo Fisher Scientific, the world leader in serving science, today announced the expansion of its Fisher BioServices cryogenic service capabilities in Japan. This expansion enables its customers to seamlessly conduct clinical trials across multiple geographies and provides patients around the world with access to life changing therapies. As a leading service provider to the cell and gene therapy community, Fisher BioServices is uniquely positioned…
Sartorius Stedim Biotech launches two Single-use Sartocon® Loop Assemblies with Integrated Polyethersulfone (PESU) Membrane
Sartorius Stedim Biotech (SSB), a leading international supplier for the biopharmaceutical industry, today announced its polyethersulfone membrane (PESU) is now integrated into two new, sterile Sartocon® benchtop and production scale filtration assemblies. Using these assemblies guarantees rapid and safe ultrafiltration of biologics and vaccines. Due to the fully enclosed design, the Sartocon® assemblies are ideal for safely purifying vaccines and recombinant proteins, as well as monoclonal antibody manufacturing. This makes them suitable for use in cGMP environments for process development,…
Practical Aspects of Implementing Continuous Bioprocessing
This webcast features: Dr. Marc Bisschops, Principal Scientist, and Dr. Mark Schofield, Principal Engineer, R&D, Pall Life Sciences The next evolution in the biopharmaceutical industry is the widespread adoption of integrated continuous bioprocessing for biologics manufacturing. The key to its success, however, is the availability of novel upstream and downstream technologies that will not only reduce facility footprint, capital expenses, and product cost of goods, but will also increase process productivity, flexibility, and further facilitate the utilization of single-use and/or…
JSR Life Sciences Acquires Exclusive Rights to SPF Technologies’ Chromassette® Platform
JSR Life Sciences has signed a technology licensing and joint development agreement for the Chromassette® technology with SPF Technologies, LLC, a private Somerville, MA-based company providing innovative solutions for biopharmaceutical manufacturing. “As a materials company that is breaking into the Life Sciences, we are continually looking for new technologies and trying to identify future trends,†said Eric R. Johnson, President of JSR Life Sciences. “We see great potential for the Chromassette technology and its impact on the bioprocessing industry.†The…
How to Boost Profits with Single-Use Powder Transfer in Biopharmaceuticals Manufacturing
For many years, media and buffer ingredients used in powder form were transferred from stock containers using open scoops, weighed and mixed in buckets or open-top bags, and then carried in and dumped from those buckets or open-top bags directly into production vessels—based on the premise that sterility wasn’t required at that early stage of manufacturing. While much of this process was often carried out in a separate room from the production line to contain airborne contaminants, final transfer to…