MilliporeSigma,announced today that the company will sponsor the Startup Program at LabCentral, a biotechnology incubator, in Cambridge, Massachusetts. LabCentral is a private, non-profit organization that provides entrepreneurs and innovative life-sciences startups with lab space and resources to nurture the next generation of biotech companies. It comprises approximately 125 scientists and entrepreneurs. MilliporeSigma’s collaboration with LabCentral, like its ongoing Emerging Biotech grant program, gives biotech startups access to process development tools, education programs and training to support their success and strengthen…
Author Archives: BPI Contributor
Synergizing Transient and Stable Protein Expression for Accelerated Biotherapeutic Development
This webcast features:Â Krista Steger, PhD, Scientist, MaxCyte Transitioning early stage discovery efforts with later stage development activities is critical for moving biological therapies into the clinic in an efficient and timely manner. MaxCyte’s scalable Flow Electroporation™ Technology allows gram-scale transient expression of antibodies and other proteins in cell types that are relevant to biomanufacturing. At the same time, the high levels of efficiency and viability provided by MaxCyte transfection, can shorten timelines and reduce labor involved in generating clonal cell…
Distek, Inc. Releases Model 2500 Select Bathless Dissolution Tester
Distek, Inc., has released the Model 2500 Select – Bathless Dissolution Tester. The patented bathless technology eliminates the water bath and all associated maintenance while heater jackets raise media temperature from ambient to 37°C in less than 15 minutes. Wireless in-shaft temperature sensors continuously monitor and display the in-vessel temperature for each vessel. A brilliant touch screen and unparalleled command of the instrument with electronic tracking of serialized stirring elements, qualification status and due dates and extensive reporting and method…
Enzo Life Sciences Introduces Innovative Ultra-Sensitive Multiplex IHC Kit
Enzo Life Sciences has released a new immunohistochemistry product, MULTIVIEW® PLUS (mouse-HRP/rabbit-AP) IHC Kit (Brown/Green). This non-biotin nanopolymer detection system contains reagents and materials that detect and localize antigens in formalin-fixed paraffin-embedded tissues. The MULTIVIEW PLUS IHC kit optimizes IHC processes by including the entire workflow, from antigen retrieval to visualization. The MULTIVIEW PLUS system can detect multiple antigens on a single tissue sample, while eliminating the traditional two-step method using biotin/avidin conjugates. The high sensitivity, low background reagents are…
Multi-Gram Scale Antibody Production Using CHO Cell Transient Gene Expression (TGE) via Flow Electroporationâ„¢ Technology
Despite advances in transfection methods and culture optimization, many CHO-based TGE systems produce insufficient antibody titers (low mg/L level) for full use within biotherapeutic development pipelines. The high productivity of MaxCyte-driven transient gene expression allows for its use in early phase candidate identification as well as for generating the gram-level antibody quantities needed for later stage pharmacology, stability and manufacturing studies. In this white paper, data are presented demonstrating the reproducibility, scalability and antibody production capabilities of MaxCyte Flow Electroporationâ„¢…
Qosina Trading Company Limited and HNG Medical, Inc. Deliver Components in China
Qosina has announced the establishment of a wholly owned China entity (柯æ€çº³), Qosina Trading Company Limited. Located in Shanghai, this office provides customers the benefit of delivering goods manufactured in China directly to their operations in China, reducing or eliminating related logistics and customs expenses. Along with a local partner for distribution, HNG Medical, Inc., Qosina can serve global customers with their China operations.
Ajinomoto Althea, Inc. Appoints Dr. Lori McDonald as Vice President of Compliance
Ajinomoto Althea, Inc., a leading contract development and manufacturing service organization, announced today it is appointing Dr. Lori McDonald as Vice President of Compliance at Althea. Althea’s contract manufacturing business continues to grow at a rapid rate driven by biotech companies outsourcing aseptic fill and finish parenteral manufacturing for clinical through commercial programs. Althea’s business has grown 25% annually since its acquisition by Ajinomoto in 2013. In 2016 alone, Althea increased its overall new business by 35%. To accommodate this…
Advanced Materials for Single-Use Biomanufacturing Systems
This webcast features: Michael W. Johnson, Business Development Engineering Manager, Life Sciences, Entegris Utilizing advanced fluoropolymer materials in single-use systems has distinct advantages in regards to extractables, chemical compatibility and cold temperature performance. This webcast examines data obtained from pilot scale testing of a new fluoropolymer single-use bag system for the freezing, storage and shipping of formulated bulk biopharmaceutical product.  You will learn: What material has the widest temperature profile from +200 to -200°C Which film material (LDPE, Polyolefin, EVAM,…
c-LEcta’s DENARASE® Removes Nucleic Acids in Pharmaceutical Processes
c-LEcta, a German biotech company located in Leipzig, has developed an advanced nuclease product, DENARASE®, designed for nucleic acid removal in biopharmaceutical production processes. Unlike other nuclease types, which usually are produced using Escherichia coli as expression host, c-LEcta’s DENARASE is manufactured using a patent protected production process based on a Bacillus strain and a fermentation medium free of any antibiotics and animal derived products.  Beside the absence of endotoxins in gram-positive bacteria like Bacillus and the absence of antibiotics…
Implementing Global Best Practices and Technology Specifications for Single-Use Systems
As global markets become more and more important, so does global manufacturing. But when your company has several manufacturing sites across the world it can be difficult to streamline efforts, manage costs and share valuable information. Our recent white paper “Implementing global best practices and technology specifications for single-use systems†tackles the issues of multinational drug manufacturing and offers several best practices that can help you cut your time to market, lower probability of process troubleshooting during start-up and decrease…