Author Archives: J. Hüttmann

Filtration Solutions for Endotoxin Reduction

PURAFIX ET-R depth-filter sheets are used for efficient and economical reduction of endotoxins from pharmaceutical liquids. Removal of endotoxins is one of the most important and challenging steps in biopharmaceutical processes. Endotoxins — more precisely, lipopolysaccharides (LPS) — are extremely heat and pH stable and therefore withstand sterilization. Purification usually is performed by applying chromatography as a polishing step, which is costly and time consuming. By reducing endotoxin load at an early stage of a clarification process, subsequent purification steps…