Josh Hays (upstream technology director, MilliporeSigma), BPI Theater @ INTERPHEX, April 26, 2016, 1:20–1:40 pm Over the past 10 years, upstream processing has undergone a considerable evolution. Single-use technologies up to the 2,000-L scale have become the “gold standard” to deliver a fast, flexible, and cost-effective solution for production of recombinant proteins in a current good manufacturing practice (CGMP) environment. Cell culture media advances through speed and flexibility enhancements as raw-material modifications (along with supply continuity and reduced overall cost…