In recent years, single-use technology has been migrating into many unit operations. With the commercial availability of such systems end users have a new option for process development and production that does not rely on operational complexities and utility requirements of conventional sterilize-in-place (SIP) or autoclavable systems. However, just as for cell culture processes, single-use technology may not apply to each and every fermentation or microbial process. It is the responsibility of practitioners to properly assess their own applications, select…