Protein A affinity chromatography continues to be the preferred method for commercial purification of antibodies due to its very high selectivity and robust resin performance over repeated purification cycles. It is now estimated that over US$125 billion of yearly sales will be generated from monoclonal antibody (MAb) products by 2020 (1). The clear majority will be purified by large-scale protein A affinity chromatography. With the continued growth and therapeutic commercial importance of MAb production, the availability of high-quality resin material…