Author Archives: Igor Fisch

Speed Matters: Gene to GMP in Nine Months

Igor Fisch, chief executive officer, Selexis, SA Fisch first posed this question: “How can we accelerate the number of drugs going into the clinics?†Speed matters because the faster a drug can get into clinical testing, the faster it can make it to market. He discussed both Selexis and KBI Biopharma and their collaboration, which started in 2012 when KBI developed a heterodimer purification process. JSR acquired both companies with an interest in entering the life sciences business. Selexis has…

Rapid Production of Functional Proteins of a Combinatorial IgG Library in CHO Cells

Recombinant DNA (rDNA) technologies provide a wide range of tools for producing a broad array of recombinant proteins. Since the early 1970s, the biotechnology industry has harnessed those tools — together with genetic engineering and genomics — for developing new classes of innovative and effective therapeutic molecules. The therapeutic recombinant protein market segment now represents the core of the medical biotechnology industry, with hundreds of companies involved in discovery, development, and marketing. Although recombinant technologies are extremely powerful tools, significant…