Friday, February 18, 2022 Daily Archives

eBook: Gene Therapies —
Developers Slowly Emerge from a Pandemic

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This eBook gauges shifting expectations for the gene therapy industry amid the COVID-related uncertainties and clinical setbacks of the past couple years. BioProcess Insider founding editor Dan Stanton reports on the January 2022 Phacilitate Advanced Therapies Week event, specifically a standing presentation on the 10 most important industry drivers from the past year. Since 2017, advancements in gene therapies have featured prominently in these presentations. In 2021, gene therapies again made the list, but this time for more troubling reasons,…

February 18, 2022

Promoter Discovery for Optimized Viral Vector Development

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This webcast features: David W. Brighty, PhD, Head of Bioprocessing Research at OXGENE, WuXi Advanced Therapies. A primary determinant of gene expression is invariably the activity of the promoter upstream of the regulated gene. Viral vectors used to deliver a therapeutic transgene into target cells to treat disease are no exception. For viral vectors, the promoters used to drive transgene expression are typically constitutively active, often display little tissue-specificity, and frequently fail to express the therapeutic transgene at optimum physiological…

February 18, 2022

Catalent eyeing up Bloomington expansion

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Catalent could potentially invest $350 million to expand its Bloomington, Indiana plant adding 1000 jobs at the site by 2026. According to various publications, including B Square Bulletin, contract development manufacturing organization (CDMO) Catalent is looking to spend $350 million at its Bloomington, Indiana facility with the City of Bloomington supposedly offering the firm millions of dollars in tax breaks. The city council is said to have unanimously voted in favour of the tax breaks this Wednesday, but a further…

February 18, 2022