Wednesday, May 26, 2021 Daily Archives

Avid secures commercial manufacturing contract for ADC’s Zynlonta

ADC Therapeutics’ recently approved cancer treatment Zynlonta will be commercially manufactured by Avid Bioservices in Tustin, California.   Contract development manufacturing organization (CDMO) Avid Bioservices will manufacture the monoclonal antibody portion of the antibody-drug conjugate (ADC) Zynlonta (loncastuximab tesirine), which received US Food and Drug Administration (FDA) approval in April. Avid has provided ADC Therapeutics with clinical manufacturing services since 2017. However, the firm will now undertake commercial manufacturing activities for Zynlonta, which is used to treat patients with relapsed or…

The Unique Benefits of Presterilized Fluoropolymer Bottles: Case Studies in Vaccine Delivery Applications

This webcast features: Eric Isberg, Vice President, Life Sciences, Savillex Fluoropolymers are the ultimate materials for use in bioprocess applications, providing increased purity, compatibility, inertness, and security for process fluids and bulk product. Bottles and vials manufactured from fluoropolymers have the added benefits of having virtually no leachables and extractables, a very wide service temperature range including performance down to liquid nitrogen temperatures, and unmatched durability, including being essentially unbreakable during use. This presentation will highlight the benefits of presterilized…

Korean CDMOs come into play to support global COVID-19 supply

Moderna has inked a deal with Samsung Biologics and Novavax has signed a memorandum of understanding with SK bioscience to provide global access to their vaccines. Novavax has not yet received authorization for its recombinant protein COVID-19 vaccine candidate NVX-CoV2373 but it is prepping for commercialization, signing a non-binding memorandum of understanding (MoU) with the Ministry of Health and Welfare of Korea and contract development manufacturing organization (CDMO) SK bioscience. Under the terms of the agreement, SK bioscience will continue…

Alvotech latest to challenge AbbVie on US Humira exclusivity

AbbVie is confident that no biosimilar will challenge Humira sales in the US until 2023 despite a legal challenge from Alvotech seeking to end the monopoly. Humira (adalimumab) is the world’s top selling drug, pulling in $19.8 billion in revenues for AbbVie in 2020. Of this, $16.1 billion was from the US, a region currently protected from adalimumab competition due to AbbVie’s web of patents and legal agreements with numerous biosimilar makers. But while the likes of Amgen, Samsung Bioepis,…