Wednesday, October 7, 2020 Daily Archives

To Compress or Not to Compress: What You Need to Know About Packing Resins at Process Scale

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This webcast features: Dr. Mark A. Snyder, Manager, Process Chromatography, R&D Applications Group, Bio-Rad Laboratories Join our expert, Dr. Mark A. Snyder, to learn best practices and guidelines for successfully packing different types of chromatography resins. This includes incompressible resins like CHT Ceramic Hydroxyapatite Media as well as traditional compressible resins. CHT is an easy-to-use mixed-mode media and has high specific gravity, a rapid settling rate, and sensitivity to mechanical shear. These variations from traditional compressible resins have to be…

October 7, 2020

Aji Bio receives FDA approval for commercial oligo process

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Ajinomoto Bio-Pharma Services’ AJIPHASE Technology has received US FDA approval for an undisclosed commercial oligonucleotide, most likely NS Pharma’s Viltepso (viltolarsen). The announcement highlights Aji’s AJIPHASE synthesis technology in its potential to scale up oligonucleotide production. “AJIPHASE is used in the development and cGMP manufacture of large-scale oligonucleotides and peptides,†a spokesperson from the company told this publication. “The AJIPHASE technology employs the use of an anchor, instead of a resin, which provides a homogeneous mixture. After the reaction occurs,…

October 7, 2020