Cross flow filtration used in bioprocesses is typically either microfiltration to clarify process streams or ultrafiltration to concentrate and diafilter the biopharmaceutical molecule. Single-use cross flow operations provide a number of advantages over traditional stainless steel systems.

These include:

• Flexibility during process development • Reduced capital investment • Avoidance of cross contamination and faster product change overs • Elimination of steaming and cleaning utilities

Parker domnick hunter’s innovative SciFlex® TFF system utilizes propriety technology allowing the sterile processing of biopharmaceutical product streams within an easy-to-learn and use system targeted at pilot plant operations and small scale manufacturing within the biopharmaceutical facility.