Eppendorf says it will continue investing in production capabilities and infrastructure as it reports a record 12 months. German life sciences tool provider Eppendorf reported revenues of €967 million($1.16 billion) for its fiscal year 2020, up 20.3% on the year prior. “2020 was by far the most successful fiscal year for the Eppendorf Group,†co-CEOs Eva van Pelt and Peter Fruhstorfer said in a joint statement. Like many of its fellow bioprocess suppliers, growth in sales across many of Eppendorf’s…
Upstream & Downstream Processing
SBI hoping to kickstart digital bioprocessing revolution through aquila buy
Scientific Bioprocessing (SBI) says it is aiming to create a digital platform to enhance biopharmaceutical workflow through the acquisition of smart sensor and data analytics firm aquila biolabs. Life sciences tool supplier Scientific Industries, through its subsidiary SBI, has acquired aquila biolabs, adding smart sensors and data analytics software for bioprocessing along with facilities in Baesweiler, Germany. “From the earliest interactions with the aquila biolabs team, it became really apparent that we shared the vision of developing technologies that can…
Avantor upping single-use capacity by 30% in response to huge demand
Avantor says investments in facilities in North Carolina, Massachusetts, and The Netherlands will help feed the surge in demand for single-use equipment driven by a robust biologics sector and the COVID-19 pandemic. Sean DeFusco, general manager of single-use solutions/fluid handling at Avantor, told BioProcess Insider the firm will increase its single-use manufacturing footprint by 30% in the United States and Europe along with doubling cleanroom space. “So far, we expanded our Morrisville, North Carolina single-use facility and we’re nearing completion…
Single-use lead times up to 12 months as COVID takes its toll
Some biomanufacturers are waiting up to a year for single-use equipment, according to ABEC. And while vendors are expanding capacity these projects will take months to come online. Early in the COVID-19 pandemic, single-use bioprocess systems and materials were highlighted as necessary tools in the development and commercial manufacture of potential vaccines and therapies. The speed and flexibility needed to make novel vaccines, including mRNA, DNA, and viral vectors, meant those platforms were largely built on single-use technologies. Coupled with…
Vendors continuing to reap the COVID windfall
Danaher expects COVID-19 vaccine and therapy-related revenue for its bioprocess businesses Pall and Cytiva to reach $2 billion, while the pandemic fuelled “an exceptionally strong start†to Sartorius’s 2021. In June last year, the evolving coronavirus pandemic was marked out as a $14 billion opportunity for bioprocess vendors by analysts. Ten months on, with several vaccines and therapies being used commercially and several more moving through the clinic, the service firms are experiencing unprecedented demand for their equipment and tools…
Oxford Biomedica working to optimize vector production platform
Oxford Biomedica is optimizing its vector production system to boost yields and accelerate production in response to growing demand. The UK gene and gene therapy firm and contract development and manufacturing organization (CDMO) talked about efforts to improve its vector production platform last week during its Q4 presentation. The main aim – according to chief scientific officer Kyri Mitrophanous – is to increase viral vector production capacity and remain competitive. “We continue to invest in the lentiviral vector platform in…
Preparation key to gene therapy commercialization, MilliporeSigma
Gene therapy firms are under pressure to get to market quickly according to an expert from MilliporeSigma, who says process development and tech transfer are significant hurdles. The ability to treat – or cure – disease at the genetic level in a targeted manner is an attractive proposition for drug companies. The challenge now is to make these therapies in a cost and time efficient manner according to Ratish Krishnan, associate director for cell and gene therapy bioprocessing at Milliporesigma.…
BPI West: Modular tech key to rapid COVID-19 vaccine development
The coronavirus pandemic has underlined the benefits of modular manufacturing according to an expert who says the approach has been key to accelerating vaccine production. SARS-CoV-2, the virus that causes COVID-19, was first isolated in December 2019 and sequenced a month later. The first vaccines against it were developed, tested, and approved about a year after the first was identified. The record speed with which industry created the COVID-19 shots is testament to vaccine industry efforts, according to John Yoshi…
CGT firms making progress but manufacturing remains a hurdle, says analyst
Cell and gene therapy developers have yet to address delivery, production and safety challenges but progress is being made. The conclusion came from RBC Capital Markets, which published analysis of trends in the cell and gene therapy sectors this week. According to executives quizzed by the market research firm, the biggest challenges that modern gene therapy firms face are pretty similar to those encountered by pioneers in the field a couple of decades ago. “Gene therapies hold considerable promise in…
Podcast: Thermo Fisher on aseptic manufacturing in the time of COVID
In the latest episode of the BioProcess Insider Expression Platform, Thermo Fisher Scientific’s Vincenza Pironti discusses how vaccine and biologic makers can ensure a robust, global fill/finish supply both during the COVID pandemic and beyond. Vincenza Pironti – Global SME, Steriles, ThermoFisher Scientific – sat down (at a distance) with editor Dan Stanton to discuss aseptic manufacturing in the current climate as part of this year’s BIO-Europe Spring. The event took place last week, but if you missed it the…