Novo Nordisk will invest $2.5 billion to construct three manufacturing facilities and expand its Kalundborg, Denmark site. According to Danish drugmaker Novo Nordisk, the expansion will support production of Novo Nordisk’s current and future injectable and oral products, including insulin. A spokesperson for Novo Nordisk told BioProcess Insider its Kalundborg site has been selected because the firm has “more than 50 years’ experience out of Kalundborg in Denmark; about 50 % of the total insulin production comes from Kalundborg; we…
Facilities & Capacity
Evolve to build plasma plant in Texas
Evolve Biologics has chosen Sachse, Texas as the site of its first plasma-derived therapeutics facility. Canadian-headquartered firm Evolve says the site selection and purchase of land establishes the company’s drive towards the commercialization of plasma-derived therapeutics. “Northern Texas has a growing corporate/pharmaceutical presence which enables collaboration and attracts a highly skilled workforce. The Dalls Fort Worth area also has a very strong educational base, including many high caliber and local universities, which is great for recruiting,†said David Holliday, Chief…
GenScript opens plasmid facility in China
GenScript has opened its plasmid manufacturing plant in Zhenjiang, China, which will provide customers with a one-stop service, says firm. According to GenScript ProBio, its second plasmid facility is the largest one in China with a total floor space of 6,400 square-meter, which will support development of cell and gene therapies and messenger RNA (mRNA) drugs. Additionally, the firm claim the plant establishes its position in the contract development manufacturing organization (CDMO) field – providing more than double plasmid production…
WuXi ATU opens Philly cell and gene therapy testing center
WuXi ATU has opened a testing facility in Philadelphia, US to cater for growing demand for the cell and gene therapy sector. The new test center expands the campus that WuXi ATU – a subsidiary of WuXi AppTec – established late in 2020. A company spokesman told us “The new Philadelphia facility will enable us to triple our capacity for critical tests related to the characterization of lentivirus and adeno-associated-virus (AAV) products such as replication competency (RCL and RCAAV assays)…
Fujifilm to invest $500m+ in UK CDMO business
Fujifilm Corp has confirmed £400 ($532) million of a previously announced investment program will be spent expanding its CDMO operations in Billingham, UK. According to a plan unveiled today Fujifilm will double the sites development and manufacturing capabilities, establish both a viral gene therapy facility and a mammalian cell culture facility and create up to 350 jobs. Fujifilm Diosynth Biotechnologies will also build a cell culture facility and ramp up antibody-based therapeutics production capacity through the addition of four 2,000…
Global microbial capacity to reach 575kL by 2025
Microbial manufacturing capacity will see steady growth over the next few years as molecular pipelines become more heterogenous, say experts. According to biotechnology group BDO’s Fall 2021 bioTRAK report covering the supply and demand of manufacturing capacity for recombinant biopharmaceuticals, current microbial manufacturing capacity totals more than 500kL. There are over 90 companies actively producing products for the global marketplace from 112 manufacturing plants, Dawn Ecker, managing director, bioTRAK Database Services told us. And “looking forward to 2025, microbial capacity…
BioMagnetic Solutions to build multi-million-dollar Pennsylvania plant
BioMagnetic Solutions will build a ferrofluid and monoclonal antibody production facility at Innovation Park in Pennsylvania, US. Â Gamma Biosciences acquired cell selection and bioseparation firm BioMagnetic Solutions (BMS) in January. Now BMS will construct a 13,000 square-foot production facility in Innovation Park at Penn State, which is expected to be fully operation in mid-2022. BMS claims the company will continue to focus on developing proprietary nanoscale ferrofluids from clinical to development through to commercial scale and the facility will…
CureVac reallocating failed COVID vax capacity to support next-gen mRNA
Having abandoned its COVID-19 candidate CVnCoV, CureVac has switched up its manufacturing network in preparation for a second-generation messenger RNA (mRNA) vaccine. For the third quarter 2021, German biotech CureVac reported a loss of €143.5 million ($162 million) – a €106.4 million increase compared to the same period in 2020. According to the firm, the increase was in line with high development costs of CVnCoV, the firm’s first-generation mRNA vaccine targeting COVID-19. This was propped up due to a change…
Lonza to expand microbial services at Swiss facility
The expansion at its Visp, Switzerland facility will support increased capacity of development services targeting microbial-derived proteins, says Lonza. The expansion will see Swiss contract development manufacturing organization (CDMO) Lonza up its microbial development laboratories at its Visp site by 50% as part of the firm’s focus on increasing its microbial service offerings. The investment, of which financial details have not been disclosed, will include the installation of a pilot suite with a 50 L fermenter and downstream equipment to…
CBM: SK investment to fund next growth phase for ambitious CDMO
The Center for Breakthrough Medicines (CBM) has taken an undisclosed amount from Korean investment firm SK Inc in its latest push to become the world’s largest cell and gene CDMO. In early 2020, life science and real estate investment company MLP Ventures and the Discovery Labs set-up CBM through a 680,000 square-foot facility at a former GSK R&D campus in King of Prussia, Pennsylvania. At the time, Brian O’Neill, founder of the Discovery Labs, said through $1.2 billion of funding…