Facilities & Capacity

Fujifilm breaks ground on 160,000 L mammalian plant in NC

Fujifilm Diosynth’s CEO Martin Meeson sees no slowdown in demand for CDMO capacity across all modalities as work begins on a $1.8 billion mammalian cell culture plant in North Carolina. In March, contract development and manufacturing organization (CDMO) Fujifilm Diosynth Biotechnologies selected Holly Springs, North Carolina as the site of its latest addition to its biomanufacturing network. Construction began last week on the Â¥200 billion ($1.8 billion), and once operational in 2025 it will offer biopharma customers 8 x 20,000…

Touchlight doubles funding and breaks ground on DNA facility

Touchlight has received the first phase of planning approval for its manufacturing facility in Hampton, UK and extended its funding round to $125 million. Hampton, UK-based firm Touchlight announced in March it had raised £42 million ($58 million) through a fundraising round led by Bridford Investments Limited, which would see the firm expand its London facility. Now, the company has extended its fundraising to a total of £92 million ($125 million) on the back of increased demand for its synthetic…

MilliporeSigma opens $110m gene therapy plant

MilliporeSigma has opened its second Carlsbad, California-based facility to support large-scale manufacturing for viral gene therapies. The life sciences services division of Merck KGaA, MilliporeSigma, announced its plans to invest $110 million to construct a second facility at its Carlsbad site in April 2020 as part of its gene therapy contract development manufacturing organization (CDMO) business. Now the firm has opened its doors to the 140,000 square-foot facility, which MilliporeSigma says will more than double its capacity to support large-scale industrial…

Months after Cognate buy, Charles River divests plasmid DNA plant

Charles River says the divestment of a plasmid DNA CDMO facility in Sweden will help optimize its business and does not signify a U-turn in its cell and gene therapy strategy. In February this year, Charles River Laboratories agreed to pay $875 million in cash to acquire Cognate BioServices. The deal propelled the biopharma services firm into the contract development and manufacturing organization (CDMO) space, adding a network of cell therapy and plasmid DNA manufacturing facilities. The deal went through…

Sheffield University to build gene therapy facility

The construction of a gene therapy facility in Sheffield, UK will advance scientific discoveries into treatment options for patients, says University. The Gene Therapy Innovation and Manufacturing Centre (GTIMC) is one of three hubs, which are part of an £18 million ($24 million) network funded by the Medical Research Council (MRC), LifeArc, and supported by the Biotechnology and Biological Sciences Research Council (BBSRC). The other two hubs are located at Kings College London and NHS Blood and Transplant in Bristol…

Avid turns to viral vector production on back of strong CGT growth

CDMO Avid Bioservices will expand its biomanufacturing services to include viral vector development and production, investing up to $75 million in a California facility. Biologics contract development and manufacturing organization (CDMO) Avid Bioservices revealed today to build a 53,000 square foot viral vector development and GMP manufacturing facility in Costa Mesa, California at a cost of between $65 million to $75 million. The facility, which could be operational within two years, will initially support projects up to 200 L using…

Lonza ups mammalian cell services in Singapore

The increased capabilities in Singapore will support both upstream and downstream processing and analytical development, the CDMO says. The size of the investment has not been disclosed, but Jeetendra Vaghjiani, senior director of Clinical Development for Mammalian Biologics, Lonza told this publication the expansion consists of a 1800 m2 lab built at the Singapore Science Park in Tuas along with the renovation of an existing 1500 m2 lab. “We are adding more capacity across all our technologies, supporting upstream and…

Boosters and beyond: CDMOs likely to continue to ride COVID-19 wave

Inoculating children and booster jabs will further fuel CDMO demand argues GlobalData’s Fiona Barry, who adds industry’s reliance on third-party manufacturers will not abate post-pandemic. Since the start of the pandemic, biopharma’s efforts and determination in developing and producing billions of vaccines and therapeutics have led to some companies and sectors benefitting from a COVID-19 windfall. The contract development and manufacturing organization (CDMO) sector is one such group, with both drug substance and drug product capacity proving crucial in the…

Boehringer opens $800m plant with 185,000 L bioreactor capacity

Boehringer Ingelheim’s biologics facility in Vienna, Austria boasts 48 bioreactors to support both its own products and its CDMO business. It has been six years in the making, but German drugmaker Boehringer Ingelheim inaugurated its latest site this week, opening the doors on its Large Scale Cell Culture (LSCC) biologics manufacturing plant in Vienna, Austria. The facility boasts a total of 48 stainless-steel bioreactors at various scales, including nine 15,000 L tanks, along with digitalization and automation technologies, and artificial…

Moderna lays plans for $500m African mRNA plant

Details remain under wraps, but the $500 million investment will lead to Moderna’s first biomanufacturing facility outside of North America. Moderna, which sprang to the forefront of biopharma on the back of the success of its COVID-19 vaccine, announced yesterday it will invest up to $500 million into a facility on the African continent to support production of its messenger RNA portfolio. While the exact location (Africa is a big place!) has not yet been decided, a spokesperson for the…