Deal-Making

Trouble choosing? BrevisRefero launches CDMO proposal platform

BrevisRefero has launched a Request For Proposal (RFP) platform aimed at helping biopharma better select its third-party manufacturing partners. The pharma world has for years relied on outsourcing partners. Contract research organizations (CROs) are used to carry out clinical trials, third parties manage transport and logistics, and of course contract development and manufacturing organizations (CDMOs) support production of nearly every component of the drug production process. Now the biopharma space can outsource the outsourcing process itself, through an online RFP…

Samsung Bio lands MAb development contract with STCube

Samsung Biologics has landed another development project when STCube asked it to help it with a cancer monoclonal antibody candidate. The South Korean contract development and manufacturing organization (CDMO) will provide cell line and process development services. It will also manufacture material for preclinical development and human trials. The monoclonal antibody in question targets an unspecified protein – called STT-003 by STCube – that is found on the surfaces of cancer cells. According to STCube, because cancer cells express high…

Thermo’s $11.5bn bid for Qiagen accepted

Thermo Fisher Scientific is poised to add coronavirus SARS-CoV-2 test kit to its diagnostics business after agreeing an $11.5bn takeover of Qiagen NV. The firms announced the agreement on Tuesday, valuing Qiagen at $11.5 billion, or €39 ($43.4) per share. Thermo CEO Marc N. Casper said, “This acquisition provides us with the opportunity to leverage our industry-leading capabilities and R&D expertise to accelerate innovation and address emerging healthcare needs. “For shareholders, we expect the transaction to be immediately accretive and…

Gilead: $4.9bn Forty Seven buy sits in the oncology ‘sweet spot’

The acquisition of monoclonal antibody developer Forty Seven complements Kite’s CAR-T therapy franchise in targeting cancers, says Gilead. Under deal terms announced Monday, Gilead will pay $95.50 (€85.50) for each share of Menlo Park, California-based Forty Seven, totaling $4.9 billion. Forty Seven’s lead CD47-blocking drug, an antibody called magrolimab, is being tested in combination with chemotherapy in separate studies evaluating it as a treatment for two types of blood cancer: a group of disorders called myelodysplastic syndromes (MDS) and acute…

Fujifilm breaks ground at $54m NC biologics plant expansion

The expansion at a cell culture facility in Research Triangle Park will feed the demand for growing biologics pipelines, says CDMO Fujifilm Diosynth Biotechnologies. Contract development and manufacturing organization (CDMO) Fujifilm broke ground on a 31,778 square-foot extension at its site in Research Triangle Park, Morrisville, North Carolina, which will add recovery and purification suites to support biomanufacturing. The firm says it will increase its cell culture manufacturing capacity by approximately 25% and microbial capacity by approximately 50% when the…

Another WuXi Vaccines deal? No, just a repurposed press release

Contrary to some reports, WuXi Biologics is not building a second facility for its recently formed vaccines joint venture but has merely secured the $3 billion contract announced last May. Nine months ago, WuXi Biologics and Shanghai-based Hile Bio-Technology formed WuXi Vaccines, a contract development and manufacturing organization (CDMO) to service a Letter of Intent (LOI) inked with an undisclosed multinational vaccine company. In November, plans were laid to build a $240 million (€222 million) three-story dedicated manufacturing facility in…

KKR pumps €50m into Univercells through Gamma funding platform

Over a quarter of Gamma Bioscience’s $200 million funding for next-generation bioprocessing technologies will be used to support Univercells’ biomanufacturing tech platforms. In January, global investment firm KKR launched Gamma Bioscience, a portfolio of life sciences tools subsidiaries. The first company to fall under the umbrella was Astrea Bioseparations, a ligand discovery and adsorbent development services firm, previously known as Prometic Bioseparations, acquired by KKR for around $100 million (€93 million) in November 2019. Now KKR and co-investors have committed…

Co.don wins MukoCell contract to make urology cell therapy

MukoCell GmbH has hired Co.don AG to manufacture its autologous cell-based treatment for urological disorders. The deal will see Co.don make the product – also named MukoCell – at its recently established human cell-focused manufacturing facility in Leipzig, Germany. Matthias Meißner, Co.don director of corporate communications, told us MukoCell “is an innovative and gentle method for the surgical repair of urethral strictures.” A urethral stricture is a narrowing of the urethra caused by injury, instrumentation, infection, and certain non-infectious forms of urethritis. MukoCell…

Charles River eyeing up HemaCare expansion and more CGT acquisitions

Charles River Laboratories says it is “seriously pursuing†geographical expansion of its recently acquired HemaCare business as it assesses further opportunities in the cell and gene therapy space. In December last year, contract research organization (CRO) Charles River picked up HemaCare for $380 million, bolstering its cell therapy services portfolio. The firm predicted the acquisition would add at least $50 million to its 2020 consolidated revenue and expects revenue growth for the business to substantially increase over the next five…

Catalent’s $315m Masthercell buy: Frothy exuberance or the new CMO norm?

Catalent has completed its $315 million takeover of cell therapy manufacturer Masthercell. But is this latest CMO acquisition a sign of frothy exuberance, or consolidation of the new normal? Dark Horse Consulting’s Anthony Davies thinks the latter. Last week, Catalent announced it had entered into an agreement to buy Orgenesis’ third-party cell and gene therapy business Masthercell for $315 million (€285 million). Yesterday the deal closed, bringing autologous and allogeneic cell therapy manufacturing and analytical services to Catalent’s capabilities. The…