Rentschler Biopharma will produce recombinant hemophilia A product Obizur for Shire after acquiring the Milford facility. German contract development and manufacturing organization (CDMO) Rentschler has entered into an agreement to buy Shire’s Milford, Massachusetts manufacturing facility. The facility makes Shire’s approved product Obizur [Antihemophilic Factor (Recombinant), Porcine Sequence], and under terms of the deal Rentschler will take over production and supply directly to Shire from the plant. Financial details have not been disclosed. “Milford is a specialized site that focuses…
Deal-Making
Stilmas buys MarCor to boost global biopharma water biz
Stilmas Americas has been formed from the acquisition of Canada’s MarCor, bringing its purified water and water for injection (WFI) solutions to North America. The deal sees Stilmas add the high purity division of MarCor to its business. Finanacial details have not been divulged. Stilmas is a subsidiary of the Masco Group, a conglomerate which offers engineering, pure media systems – including WFI stills, purified water systems, pure steam generators – and super skid preparation systems to the biopharma industry,…
Korea exchange: Celltrion probed as Samsung Bio resumes trading
An investigating has begun into alleged accounting irregularities between Celltrion Inc. and its affiliate Celltrion Healthcare. Meanwhile, Samsung BioLogics has recommenced share trading a month after being hit by its own accountancy problems. South Korea’s Financial Supervisory Services (FSS) is looking into the business dealings of drugmaker Celltrion Inc and its wholesaler and marketing affiliate Celltrion Healthcare, according to Korean news outlet YTN. The article claimed Celltrion Healthcare violated accounting rules by selling the domestic distribution rights of biological medicines…
PPD beefing up biologics lab services in Ireland
Contract research organization (CRO) PPD will expand its biologics capabilities in Athlone, Ireland to include cell and gene therapy analytical testing. The 41,000 square foot Athlone facility will have a further 6,000 square feet of lab space added to it to feed the demand for biologics testing and to mirror expansions being made at PPD’s facility across the pond in Middleton, Wisconsin. “The Athlone facility enables us to partner closely with a wide variety of both European and global clients…
Separate together: Biotage buying purification firm PhyNexus
Swedish separations firm Biotage will add lab scale purification technology through its acquisition of PhyNexus. Financial details of the deal have not been divulged, but the California-based private firm PhyNexus has agreed to be acquired by Biotage this week. PhyNexus will bring an enabling automation platform based on Dual Flow Chromatography to Biotage’s bioprocess offering and increase the firm’s place in the downstream space. The technology enables miniaturized and parallel automated work-flows to address different laboratory purification processes. The Dual…
Axovant looks to CDMO Yposkesi for gene therapy scale up
Axovant Sciences has selected French CDMO Yposkesi as a strategic partner to help bring its neurologic and neuromuscular gene therapy candidates through the clinic. Contract development and manufacturing organization (CDMO) Yposkesi will utilize its adeno-associated virus (AAV) and lentiviral vector production capabilities to service the strategic agreement with Axovant. Swiss biotech Axovant has a pipeline of gene therapies targeting neurological and neuromuscular diseases. Financial details have not been divulged, but Alain Lamproye, CEO of Yposkesi, said it is a straight…
Small molecule M&A round-up: Roche buys Jecure, Arsanis and X4 merge
Bored of biologics? Tired of T-cells? Well BioProcess Insider takes a look at some of the big developments in the small molecule world. First up in this compendium is Swiss pharma giant Roche. The firm has acquired San Diego, California-based Jecure Therapeutics through its Genentech division. While Genentech is synonymous with biologics, Jecure’s business focuses on small-molecule therapeutics for the treatment of non-alcoholic steatohepatitis (NASH) and liver fibrosis. Its lead candidate is an inhibitor of Nucleotide-binding oligomerization (NOD)-like Receptor Family…
GE plans purification platform production plant post Puridify purchase
GE Healthcare will open a biomanufacturing center in Stevenage, UK to support production of its fiber-based purification platform, which it acquired last year. In November 2017, bioprocessing equipment and consumables vendor GE Healthcare acquired Puridify – a spin-out from University College London, UK – for an undisclosed fee. The deal added early-stage tech platform FibroSelect, consisting of a nanofiber-based material to which ligands are attached to activate the platform for purification of biologics. A year on and the firm has…
EU gives conditional nod for Takeda Shire megamerger
The European Commission (EC) has approved Takeda’s $62 billion acquisition on the proviso the firm divests Shire’s inflammatory bowel disease (IBD) candidate. In May, Japanese firm Takeda struck a deal to acquire Ireland-headquartered rare diseases biopharmaceutical company Shire for $62 billion (€54 billion). Six months on, the merger is one step closer after receiving approval under the EU Merger Regulation, on the condition of divesting Shire’s IBD candidate SHP647. “We can today approve the merger between Shire and Takeda, but…
LG Chem teams with Cue Biopharma in $405m plus oncology deal
LG Chem Life Sciences will offer up its biomanufacturing experience and potentially add downstream capabilities for Cue Biopharma’s biologic candidates under terms of the strategic partnership. Korean chemical company LG Chem’s life science business and Massachusetts-based Cue Biopharma have entered into a multi-target strategic collaboration to develop multiple candidates using the Immuno-STAT biologic platform. Cue’s Immuno-STAT biologics are designed for targeted modulation of disease-associated T cells and lead candidate CUE-101 targets human papillomavirus (HPV)-associated cancers. Under terms of the deal,…