October 2011

Optimization, Robustness, and Scale-Up of MAb Purification

The biopharmaceutical industry needs faster and more efficient development of new drugs and their market introduction as well as shorter process development times for both upstream and downstream operations. It has become more commonplace to use high-throughput development techniques to save time (1). Development is also sped up by applying platform technologies based on the unsurpassed selectivity of protein A resins (2,3,4,5,6), which is the foundation for downstream processing of monoclonal antibodies (MAbs). This is the second of two articles…

GLOBAL MARKETPLACE

Antimicrobial Incubator Product: Multitron incubator shaker Applications: Cell line screening and seed cultures for larger validated processes Features: ATR has added an optional antimicrobial coating to the interior of its Multitron incubator shaker cabinet. This exclusively formulated coating inhibits the growth of bacteria, molds, and fungi over 100,000-fold. The coating is safe, effective, long-lasting, and approved for use in medical and food industries by independent certification. It is applied in production and can be ordered with any Multitron unit. All…

Exchanging Real-World Solutions to Improve Speed, Cost, and Predictability BioProcess International Conference & Exhibition

The BioProcess International Conference is where challenges are explored, solutions are uncovered, and opportunities are developed, making it the largest and most highly respected event solely dedicated to biopharmaceutical manufacturing. Save time and reduce cost of goods with tips on streamlining processes and implementing novel technologies. Find new collaborators and partners with superior networking opportunities at the industry’s largest event devoted solely to biopharmaceutical production. Consult with >150 providers of novel and practical services and products in the exhibit hall.…

Toward Defined Culture Conditions for Pluripotent Stem Cells, Part 1

    On 31 March 2011, ~50 delegates attended a workshop organized by STEMCELL Technologies on implications of standard defined culture conditions for embryonic and induced-pluripotent human stem cells as part of the annual meeting of the UK National Stem Cell Network in York, UK. Researchers from both academia and industry need to develop a better understanding of those implications. Our company wanted to give them a better appreciation of key challenges facing ancillary material suppliers who manufacture standard defined…