Author Archives: Scott Miller

Bioconjugation CMC: Successfully Executing a Complex Process

Scott A. Miller, senior scientific advisor, Carbogen Amcis AG Miller provided an overview of bioconjugation followed by a brief discussion of the project management aspects of this highly complex process. Developing and manufacturing antibody–drug conjufgtes (ADCs) is complicated, so it’s important to understand how to manage the processes involved. Some general considerations for developing ADCs include understanding the current phase of a project, the number and status of analytical methods required, the scale of conjugation, the sourcing of both antibody…