Clarifying cell culture broth is the first downstream unit operation in an elaborate sequence of steps required to purify a biological therapeutic. The availability of large-scale, single-use depth filtration technology in recent years has given process developers the capability to improve and simplify downstream processes. The Zeta Plus™ Encapsulated System is a single-use depth filtration system designed for the bioprocessing industry where upstream cell culture clarification or downstream impurity removal is required. The Zeta Plus Encapsulated System consists of a…