Author Archives: Millie Nelson

Q3: Sartorius says lean manufacturing drives margins

Sartorius says its focus on lean manufacturing and creating additional capacity has pushed its margins up, but increased headcount will have an impact going forward. For the first nine months of 2021, German life sciences firm Sartorius reported group sales revenue of €2.6 billion ($3 billion), an increase of 50.4% year-on-year. The firm highlighted strong demand for its bioprocessing services and consumables as a major factor in this growth, with the division contributing almost €2 billon to the top line.…

NorthX Biologics takes over Charles River Swedish plant

NorthX Biologics will take over Charles River’s manufacturing facility in Matfors, Sweden through $52 million acquisition. Seven months on from Charles River Laboratories $875 million acquisition of Cognate Bio (Cognate acquired Cobra Biologics in November 2019) the firm has offloaded one of its Cognate assets, selling a plant in Matfors, Sweden to private investor group Flerie Invest in an acquisition worth $52 million. The entity has been named North X Biologics and the 7,000 square-meter facility houses process development and…

Joint research agreement to develop viral vector tech, says Matica Bio

Matica Bio and Sartorius have entered a joint research agreement to develop advanced viral vector manufacturing technology. Matica Biotechnology, a contract development manufacturing organization (CDMO) that specializes in the clinical and commercial production of cell and gene therapies (CGTs), will work on various studies with German life sciences firm Sartorius to streamline and optimize PAT technologies, automation software, and single-use platforms offered by Sartorius for large scale vector production. According to Matica, together both companies will tackle the challenges associated…

Hansoh goes for GOLD in siRNA partnership

Hansoh Pharma will use Silence Therapeutics’ mRNAi GOLD platform to develop three undisclosed short interfering ribonucleic acids (siRNAs). According to RNA interference biotech company Silence, its mRNAi GOLD platform is  “designed to accurately target and ‘silence’ specific disease-associated genes in liver cells by using the body’s natural process of RNA interference (RNAi).†Under the terms of the agreement, Hansoh will have the exclusive option to license rights to two targets in Hong Kong, Greater China, Macau, and Taiwan following Phase…

ISCT partners to provide ‘urgent’ training programs for CGT workforce

The International Society for Cell and Gene Therapy (ISCT) and the National Science Foundation (NSF) have partnered to provide training to upskill personnel. Led by the Georgia Institute of Technology, the global collaboration between ISCT and NSF’s Engineering Research Center for Cell Manufacturing Technologies (CMaT) aims to bridge the critical skills gap in the cell and gene therapy (CGT) industry by delivering educational programs. The joint-training program entitled ‘‘Workforce Development in Biomanufacturing – A Global Partnership with ISCT and CMaTâ€,…

Terumo and BioCentriq to drive automated CGT manufacturing

BioCentriq’s laboratories will be equipped with Terumo’s technologies to accelerate the adoption of automated production for cell and gene therapies. Apheresis services firm Terumo Blood and Cell Technologies and cell and gene therapy contract development manufacturing organization (CDMO) BioCentriq have entered a strategic collaboration to bring cell and gene therapies (CGT) to individuals more quickly and cheaper. “This agreement will expand customer reach by introducing early-stage CGT researchers and developers to the benefits of manufacturing automation and demonstrating how to…

PTC opens gene therapy NJ plant

PTC Therapeutics has opened its gene therapy manufacturing facility in Hopewell, New Jersey set to support production and research operations. PTC leased the facility in July 2020 and has since invested around $20 million at the site to develop a biologics plant that supports gene therapy research and production. Now, the 220,500 square-foot facility is open and consists of office, manufacturing, and laboratory space. According to the firm, the Hopewell facility can handle process development and manufacturing services for PTC’s…

Cellectis unveils NC plant, adding in-house capabilities

Cellectis has opened its clinical and commercial manufacturing facility in Raleigh, North Carolina making it a one-stop-shop company, says firm. France-headquartered Cellectis announced plans in March 2019 to construct a clinical and commercial production plant in Raleigh, North Carolina at a reported cost of $68 million to support its allogeneic universal chimeric antigen receptor t-cells (UCART) products. The 82,000 square-foot facility has been operational for a couple of months but Cellectis did an official opening earlier this month. The gene editing…

Touchlight doubles funding and breaks ground on DNA facility

Touchlight has received the first phase of planning approval for its manufacturing facility in Hampton, UK and extended its funding round to $125 million. Hampton, UK-based firm Touchlight announced in March it had raised £42 million ($58 million) through a fundraising round led by Bridford Investments Limited, which would see the firm expand its London facility. Now, the company has extended its fundraising to a total of £92 million ($125 million) on the back of increased demand for its synthetic…

MilliporeSigma opens $110m gene therapy plant

MilliporeSigma has opened its second Carlsbad, California-based facility to support large-scale manufacturing for viral gene therapies. The life sciences services division of Merck KGaA, MilliporeSigma, announced its plans to invest $110 million to construct a second facility at its Carlsbad site in April 2020 as part of its gene therapy contract development manufacturing organization (CDMO) business. Now the firm has opened its doors to the 140,000 square-foot facility, which MilliporeSigma says will more than double its capacity to support large-scale industrial…