GenScript has opened its plasmid manufacturing plant in Zhenjiang, China, which will provide customers with a one-stop service, says firm. According to GenScript ProBio, its second plasmid facility is the largest one in China with a total floor space of 6,400 square-meter, which will support development of cell and gene therapies and messenger RNA (mRNA) drugs. Additionally, the firm claim the plant establishes its position in the contract development manufacturing organization (CDMO) field – providing more than double plasmid production…
Author Archives: Millie Nelson
Sanofi boosts vaccine pipeline with Origimm buy
Sanofi will add a potential acne vaccine candidate to its pipeline through the acquisition of Origimm Biotechnology. Sanofi is set to acquire Austrian biotechnology firm Origimm, which specializes in the discovery of virulent skin microbiome components and antigens causing skin diseases for an undisclosed fee. The move sees the French pharma giant  add a potential first-in-class vaccine candidate ORI-001 to treat acne vulgaris, a stigmatizing skin condition that affects millions of people of different ages worldwide. ORI-001 is a therapeutic…
Global microbial capacity to reach 575kL by 2025
Microbial manufacturing capacity will see steady growth over the next few years as molecular pipelines become more heterogenous, say experts. According to biotechnology group BDO’s Fall 2021 bioTRAK report covering the supply and demand of manufacturing capacity for recombinant biopharmaceuticals, current microbial manufacturing capacity totals more than 500kL. There are over 90 companies actively producing products for the global marketplace from 112 manufacturing plants, Dawn Ecker, managing director, bioTRAK Database Services told us. And “looking forward to 2025, microbial capacity…
CDMO round-up: Lonza, Abzena, and Samsung deals
BlueJay Therapeutics selects Lonza to manufacture its HBV antibody candidate; BiVictriX contracts Abzena; Samsung Biologics will manufacture drug substance for GreenLight’s mRNA COVID-19 vaccine candidate. Great to have you here for BioProcess Insider’s CDMO round-up. First up in our contract development manufacturing organization (CDMO) round-up is Swiss company Lonza, which BlueJay Therapeutics recently selected to provide a tailored program to support production of BJT-778 a monoclonal antibody (mAb) drug candidate targeting chronic hepatitis B virus (HBV) infection. Under terms of…
BioMagnetic Solutions to build multi-million-dollar Pennsylvania plant
BioMagnetic Solutions will build a ferrofluid and monoclonal antibody production facility at Innovation Park in Pennsylvania, US. Â Gamma Biosciences acquired cell selection and bioseparation firm BioMagnetic Solutions (BMS) in January. Now BMS will construct a 13,000 square-foot production facility in Innovation Park at Penn State, which is expected to be fully operation in mid-2022. BMS claims the company will continue to focus on developing proprietary nanoscale ferrofluids from clinical to development through to commercial scale and the facility will…
Ins & Outs: Filling gaps at Pfizer and the FDA
Pfizer’s chief financial officer Frank D’Amelio will retire from his position after 15 years at the firm, prompting an external search for his successor. Meanwhile, Joe Biden nominates Robert Califf for US FDA chief. Sit back, relax, and enjoy this week’s Ins &Outs. Pfizer announced D’Amelio’s planned departure from the company and stated he has agreed to stay on board in a consulting role while the firm externally search for a chief financial officer (CFO). Pfizer claim that during D’Amelio’s…
Lonza to expand microbial services at Swiss facility
The expansion at its Visp, Switzerland facility will support increased capacity of development services targeting microbial-derived proteins, says Lonza. The expansion will see Swiss contract development manufacturing organization (CDMO) Lonza up its microbial development laboratories at its Visp site by 50% as part of the firm’s focus on increasing its microbial service offerings. The investment, of which financial details have not been disclosed, will include the installation of a pilot suite with a 50 L fermenter and downstream equipment to…
eBook: Vaccines Revisited — The Past, Present, and Future of Nucleic-Acid Vaccine Production
The quarterly BioProcess Insider eBook series launched in 2021 to investigate specific modalities and business strategies driving the biopharmaceutical sector based upon trends and discussion points presented in the Insider’s pages. Two of the four quarterly publications — this one included — have focused on the vaccine industry. If the series had launched in 2019, cell and gene therapies might have warranted a double edition, or perhaps investments in antibodies and antibody fragments would have driven a bispecific focus. Five…
Baxter injects $100m to expand German fill-finish plant
Baxter Biopharma Solutions will invest $100 million to expand its fill-finish capabilities at a plant in Halle/Westfalen, Germany. The German facility is operated by Baxter Biopharma Solutions (BPS), the contract development manufacturing organization (CDMO) arm of Baxter International. The $100 million expansion will add a syringe filling line and additional lyophilized and liquid vial capacity. According to the firm, the addition of an aseptic syringe filling line will enable BPS to meet the increased demand for fill-finish services in Europe…
CGT Catapult partners to overcome barriers in ATMP industry
CGT Catapult has partnered with Deep Science Ventures to tackle issues and create companies that address needs in the advanced therapy sector. Together, the Cell and Gene Therapy Catapult (CGT Catapult) and London , UK-based venture creator Deep Science Ventures (DSV) aim to drive innovation and employment opportunities in the advanced therapy industry by addressing challenges in the sector and creating companies to support better patient outcomes. “The CGT Catapult will leverage its world-class technical and regulatory expertise in ATMPs alongside…