Learn how single-pass tangential flow filtration (SPTFF) technology is revolutionizing current and future bioprocessing platforms with its implementations in biotech, vaccine and plasma industries. Adopting SPTFF at process development (PD), pilot, clinical and commercial manufacturing scales has major advantages over conventional approaches. Key benefits include flexible manufacturing, reduced processing volumes, high product recoveries and increased yield, as well as major savings in capital expenditures. SPTFF also enables disposable and/or single-use technology utilization.
Author Archives: BPI Contributor
CHO Cell Cultivation in the Allegroâ„¢ XRS 20 Bioreactor System with Working Volumes from 2 to 25 L
The Allegroâ„¢ XRS 20 bioreactor system is a single-use bioreactor technology designed for applications ranging from general life sciences research to seed train operations, and as a final stage reactor for small scale commercial production. In practice, many installed systems have been implemented into seed train and small scale GMP production operations, where operational simplicity and consistent results are key benefits for industrial users. In the application note summarized here, we report efforts to enhance the capabilities of the…
BTEC Partners with BioProcess International to Launch Education and Training Initiative
BTEC is excited to announce a partnership with BioProcess International (BPI) to conduct a yearlong outreach campaign targeting industry leaders. The partnership will focus attention on the value added by industry-specific education, training, and professional development. Well-designed training programs can reduce human error, drive adoption of emerging technologies, and motivate a technical workforce. This message, understood by organizational development, learning management, and training professionals, will be shared with decision-makers working in operations, process development, engineering, research, and the industry’s large…
JSR Corporation Establishes JSR Life Sciences Division, Names North American Leader
JSR Corporation today announced the formation and establishment of its Life Sciences Division, JSR Life Sciences (JLS). The newly formed JLS has been established as a business unit for parent company, Tokyo-based JSR Corporation, a company with more than 50 years of success in material and polymer chemistries including marketing latex and magnetic beads to life sciences and diagnostic companies worldwide. Eric R. Johnson will lead the global operation for the Life Sciences business and assume responsibility of all operations…
Quattroflowâ„¢ Introduces QF1200HT Compact Version Quaternary Diaphragm Pump
Quattroflowâ„¢, part of PSG®, a Dover company and a leading brand of positive displacement quaternary diaphragm pumps, is pleased to announce that it has answered the needs of labs that have strict space-use requirements with the release of the QF1200HT (Compact Version) Quaternary (Four-Piston) Diaphragm Pump. Available in both Single- and Multiple-Use variations, the new QF1200HT features a high turndown ratio (200:1) and accuracy in controlling flow rates, which makes it ideal for use in a wide variety of biopharmaceutical…
Quattroflowâ„¢ Releases QF20kSU Single-Use Quaternary Diaphragm Pump
Quattroflowâ„¢, part of PSG®, a Dover company and a leading brand of positive displacement quaternary diaphragm pumps, is pleased to announce the introduction of its QF20kSU Single-Use Quaternary (Four-Piston) Diaphragm Pump. Featuring flow rates from 200 to 16,000 lph (53 to 4,227 gph), the new QF20kSU is an ideal solution for a wide variety of pharmaceutical and biotech applications. QF20kSU pumps feature a replaceable polypropylene (PP) wetted pump chamber that can be easily and quickly replaced as a complete unit…
Pall SoloHill® Animal Protein-Free Microcarriers for Dengue Virus Production
Pall Life Sciences offers a variety of regulatory-friendly animal protein-free (APF) SoloHill® microcarriers that can be quickly and easily optimized for use in vaccine production platforms. Our application note describes dengue virus production in Vero, optimizing cell culture seeding densities and microcarrier working concentrations for efficient cell attachment and growth in two different cell culture media platforms: a traditional serum supplemented formulation and a commercially available serum-free formulation (SFM). Overall, the results of this study demonstrates that Pall APF microcarriers…
Objective Characterization Data on Drug and Gene Delivery Platforms
This webcast features: Dr. Josefina Nilsson, Head of Vironova Services, as well as her colleagues, Gustaf Kylberg and Mathieu Colomb-Delsuc. Advanced analytics that provide objective and reliable data can help to improve processes and shorten development time of drug and gene delivery platforms. The use of electron microscopy (EM) imaging combined with analysis using the proprietary Vironova Analyzing Software (VAS) enables semi-automated particle detection and classification. Statistically significant results are obtained in a time and cost effective manner. Typical data…
New LED Lighting for INFORS HT Incubator Shakers
Energy-saving, high light intensity, even light distribution and long lifespan: The new LED lighting of INFORS HT incubator shakers offers much more than conventional fluorescent tubes. For the culture of photosynthetic organisms such as algae, plant cells and photosynthetic bacteria, we now rely fully on LEDs. The warm white LED light offers the ideal daylight-like spectrum in the visible range, with a very high proportion of photosynthetically active light. This universal solution ensures excellent growth of all photosensitive organisms. “In…
Brammer Bio Formed Through Merger of Brammer Biopharmaceuticals and Florida Biologix
Brammer Biopharmaceuticals today announces its merger with Florida Biologix to create the best-in-class cell and gene therapy biologics contract development and manufacturing organization (CDMO). The merged company, Brammer Bio, will combine deep technical expertise in process development and clinical manufacturing with demonstrated capabilities, operating approaches and the quality standards required for commercial manufacturing. Ampersand Capital Partners, the majority shareholder of Florida Biologix, made an additional investment in the combined company and is the only institutional investor in Brammer Bio. Brammer…