MilliporeSigma announced survey results of 250 global biopharmaceutical executives on how their companies will manage new risks associated with the changing biopharma landscape. The survey, sponsored by MilliporeSigma, was conducted by the Economist Intelligence Unit (EIU), a leading resource for economic and business research, forecasting and analysis. Findings were presented on June 8 at the 2016 BIO International Convention in San Francisco, California. “In response to the uncertainty and disruption facing the biopharmaceutical industry, MilliporeSigma has moved beyond old risk-management…
Author Archives: BPI Contributor
Lonza Announces 25th Approved Biotherapeutic Using the GS Gene Expression Systemâ„¢
Lonza, a global leader in biological development and manufacturing, announced today that with the approval of CSL Behring’s IDELVION® fusion protein for Hemophilia B Therapy, the overall number of approved biotherapeutics expressed using our GS Gene Expression Systemâ„¢ now totals 25 products. IDELVION® is the third GS expressed product approved in 2016. CSL Behring developed IDELVION® internally by taking advantage of our GS Licensing Program. They began their development work with a Research Evaluation Agreement using the materials and tools…
Finesse SmartFactoryâ„¢ Platform Featured in Alvotech Opening of New Manufacturing and Lab Facility in Iceland
The first installation of Finesse’s new SmartFactory platform was featured when Alvotech announced the opening of its state-of-the-art manufacturing and lab facility in Reykjavik, Iceland. Alvotech, Iceland’s powerful new player in biopharmaceuticals, will use this hybrid facility to rapidly expand its production capacity using multiple 1,000 L and 2,000 L single-use bioreactor trains. The facility, located at the University of Iceland Science Park, will leverage cutting-edge automation, enabling Alvotech to produce higher yields, significantly reduce labor and capital expenses, and…
Bioprocess Insights Webinars
The biopharmaceutical industry has developed into a multi-billion dollar market in just 30 years. Making decisions and setting up strategies in a rapidly changing environment can be challenging. The difference between a good and a great decision can have extensive implications for the future of a company. In this environment, knowledge and experience are what make the difference. Good insights about, for example, technical advancements, process economy implications, and sustainability aspects can help improve the individual decisions and strengthen the…
WuXi Biologics and Sartorius Stedim Biotech Open Joint Laboratory in Shanghai
Sartorius Stedim Biotech, an international leading supplier for the biopharmaceutical industry, and WuXi Biologics recently announced the opening of their Joint Laboratory in Shanghai, marking an exciting new stage in their long-term cooperation. The Joint Laboratory has been established to enhance China’s position in the global R&D of novel biologics and to facilitate more biologics to enter pilot studies and manufacture. As a result, this lab will help improve the capability and quality of biologics R&D in China and further…
Women In Bio Launches Executive-Level Certification Program to Prepare Women in Life Sciences for Board of Directors Role
Women In Bio (WIB), an organization of professionals committed to promoting careers, leadership, and entrepreneurship of women in the life sciences, today announced the launch of a new executive-level board certification training program that will prepare women in the Life Sciences to become members of Boards of Directors. The “Boardroom Ready” program will provide women with a full understanding of the duties, responsibilities and commitments of serving on both public and private boards. Graduates will also have access to events…
Distek, Inc. Releases BIOne Single-Use Bioreactor System
From the company that has brought you 40 years of excellence in laboratory pharmaceutical instruments, Distek, Inc. is proud to introduce the BIOne (pronounced “BIO Oneâ€) Single-Use Bioreactor System. Distek, Inc. has developed a benchtop scale single-use bioreactor (SUB) system for mammalian cell growth and recombinant protein production. The pre-sterilized BIOne system is engineered with a disposable headplate welded to a tri-layer liner that can be easily inserted into a non-sterile bioreactor glass vessel, converting it to a sterile, disposable…
Ten Tips for Single-Use Biopharmaceutical and Pharmaceutical Tubing Selection
Tubing for Single-Use bioprocess and pharmaceutical applications has particular requirements. Among them are the ability to withstand various sterilization processes, the delivery of favorable test results regarding extractable substances, and the absence of animal-derived ingredients. Flexibility, permeability, performance in pumps, and welding and sealing capabilities are also common considerations. Additionally, these critical industries should be aware of the environment in which the tubing is manufactured, association standards that must be met and costs. One of the most important concerns involves…
Solving Viscosity in Automated Particle Imaging
Micro-Flow Imagingâ„¢ (MFI) easily detects particle size and morphology on a wide range of particle contaminants. And when you add the Bot 1 Autosampler to your MFI 5000 Series system, you’ve got the automated go-to method of choice for particle analysis today. Together, this combination lets you quickly screen for any changes in levels of particle contaminants like protein aggregates and silicone oil in your biopharmaceutical formulation. Highly concentrated protein solutions can be a little trickier to analyze with other…
Objective characterization of liposomal drug delivery platforms: Using cryoTEM and designated image analysis software
Quality-critical attributes particular to liposome drug products include physicochemical properties such as particle size distribution and morphology, e.g. their overall shape. Such properties will influence the biological activity and bio-distribution of liposomal-based drug and gene delivery platforms. Analytical techniques that provide objective and reliable information on liposome particle characteristics can thus help to improve product development processes and shorten the time to securing their final quality. Cryo-transmission electron microscopy (cryoTEM) combined with image analysis using proprietary Vironova Analyzing Software (VAS)…