MilliporeSigma today announced that it has entered into a set of agreements with Evotec AG, whereby Evotec AG will provide screening services for Merck’s collection of genetic reagents such as CRISPR and shRNA libraries. Combining access to these libraries with Evotec’s screening expertise offers an accelerated pathway to explore and identify new drug targets. “Drug discovery starts with the identification of new targets, a process that can be time- and labor-intensive,” said Theresa Creasey, Head of Applied Solutions Strategic Marketing &…
Author Archives: BPI Contributor
Cook Regentec and Asymptote Introduce the CellSeal Automated Thawing System
Cook Regentec, focused on developing research and clinical tools to advance regenerative medicine therapies from the lab to the patient, and Asymptote Ltd., specialists in cryochain for regenerative medicine, today announced the launch of the CellSeal® Automated Thawing System. The new system, which has been developed as part of a collaboration between the two companies, provides users with thorough control in the thawing of cryogenically frozen cells, a critical step in the delivery of cell and gene therapies. The CellSeal®…
Single-use XCell ATF Systems for Continuous Processing: 100% Cell Retention, 80% Faster Set-Up
This webcast features: Christine Gebski, Vice President, Product Management and Field Applications, Repligen In today’s flexible manufacturing environments and to improve manufacturing cost of goods, many companies have implemented single-use equipment. To meet these changing customer requirements, the XCell™ ATF 2 and ATF 6 are now available in single-use formats. The XCell ATF Single-use systems deliver the same cell culture performance as the stainless steel systems but with 8x faster set-up time and a simplified autoclave-free implementation workflow. These elements…
Finesse Solutions Announces CellWorld 2017 Executive Forum
Finesse Solutions, Inc., a manufacturer of measurement and control solutions for life sciences process applications, is pleased to announce the dates and topics for CellWorld 2017, a Finesse-sponsored event designed for innovators, visionaries and senior executives in bioprocessing. This invitation-only conference will be held April 25-26, 2017 at the Hilton San Francisco Financial District. It will be a forum for life sciences leaders to discuss the future of biosimilar manufacturing and learn about both disruptive technologies and best practices for…
New Genderless Sterile Connection Technology – A Quality By Design (QbD) Approach For Greater Sterility Assurance From Manufacturing To Use
Single-use pre-sterilized systems can potentially offer a higher level of sterility assurance and a lower risk of product contamination by eliminating some of the operational procedures of traditional processing. The importance of this benefit was highlighted by the FDA’s product recalls in 2015 where 78% of recalls were attributed to lack of sterility assurance or to contamination of the drug product, with the primary reason being failure to follow written procedures. A key requirement for multi-component, single-use sterile systems is…
Sartorius Stedim Biotech Opens New Bioanalytical Testing Laboratory in Boston
Sartorius Stedim Biotech (SSB), a leading international supplier for the biopharmaceutical industry, opened a new bioanalytical and biosafety testing laboratory yesterday in the major biotech hub of Boston, Massachusetts. This dedicated bioanalytical laboratory is designed to accommodate the rising demand for the company’s BioOutsource brand specialized assay platforms in North America and facilitate the ongoing expansion of this unique service offering. At the opening ceremony, Reinhardt Vogt, member of SSB’s Executive Committee, welcomed many representatives from the biotech industry and…
Taking Medium and Feed Development Beyond Maximizing Protein Titer to Optimizing Glycan Distribution and Simplifying Process Scale-Up
This webcast features: Serena Fries Smith, Process Science Manager, Thermo Fisher Scientific In the early 2000s when many processes were struggling to achieve 1 g/L, maximizing titers was the industry’s biggest challenge and was essential to having favorable cost of goods and an economically viable product. Over the last 1–15 years, the industry has made significant advances in media and feeds. Due to these advancements, today a standard fed-batch process can typically achieve 3 g/L and some processes are achieving…
Enzo Life Sciences Launches New Immunoassay to Detect Low Levels of IL-6
Enzo Life Sciences is proud to introduce our newest immunoassay, IL-6 (human), high sensitivity ELISA kit, the most sensitive IL-6 ELISA on the market. Enzo’s new kit is able to detect IL-6 levels down to 0.057 pg/mL. In addition, our kit offers detection in 3 hours, with liquid color-coded reagents that reduce the possibility for error. From forty years of manufacturing, Enzo’s immunoassays offer high precision, accuracy, sensitivity, and specificity. IL-6 is a cytokine critical to the regulation of the…
Microbial Testing Without the Burden: New EZ-Fitâ„¢ Filtration Units from MilliporeSigma
MilliporeSigma has expanded its portfolio of EZ-Fitâ„¢ filtration units, ready-to-use, disposable filtration devices for bioburden testing. The new EZ-Fitâ„¢ filtration units come with a wide range of membrane sizes to suit all applications, and a new patented drain design to accelerate processing of turbid and hard-to-filter matrices. The full portfolio, including the new units, conforms to international standards (USP/EP) and water testing regulations, and can be used for filtration of liquid samples including water, raw materials, in-process samples and final…
CASSS and Biophysics Working Group Aim to Increase Scientific Dialogue About Biologics
CASSS has partnered with the Biophysics Working Group to support its mission to bring together scientists from across public and private sectors to address challenges in biologics research and development. The goals of the Biophysics Working Group are to provide guidance and best practices, support innovation, advance transformative ideas, and generally enhance the overall scientific dialogue through contributions in various publications and CASSS conferences around the world. This group also aligns with CASSS’s purpose to enable a global community of…