Author Archives: BPI Contributor

Purification of Antibody Fragments with Amsphere™ A3 Protein A Resin

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This webcast features: Gerald Platteau, Application Development Engineer, JSR Life sciences Purification of full-length antibodies containing an Fc region relies on Protein A affinity chromatography as the golden standard capture step. The well-known robustness, high selectivity and scalability make it an ideal platform technique, minimizing downstream processing development time to bring new antibodies to market. After monoclonal antibodies (mAbs), various forms of antibody fragments are now becoming the next most important class of protein based therapeutics. These antibody fragments offer…

September 14, 2017

Purification of Fab and scFv Using High Binding Capacity TOYOPEARL® AF-rProtein L-650F Resin

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Protein L based affinity chromatography is used for the capture of antibodies and antibody fragments that do not bind to protein A. Unlike protein A and G, which bind to the Fc region of immunoglobulins (IgGs), protein L binds through interactions with the variable region of an antibody’s kappa light chain. TOYOPEARL AF-rProtein L-650F is an affinity chromatography resin that combines a rigid polymer matrix with a recombinant protein L ligand, which is derived from the B4 domain of native…

September 14, 2017

CHT Column Packing is Easier
Than You Think

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This webcast features: Dr. Mark Snyder, Manager, R&D Applications, Process Chromatography, Bio-Rad Laboratories This webcast presents best practices and guidelines for packing CHT™ Ceramic Hydroxyapatite Media at process scale. CHT, is an easy-to-use mixed-mode chromatography media. It offers cation exchange and affinity interactions. Unlike other chromatography media, CHT is both the ligand and the support matrix. It is used for the purification of numerous types of biomolecules and is considered the gold standard for aggregate removal. This webcast highlight CHT…

September 7, 2017

GEA Unifies Controls for Separators and Decanters with GEA IO Control

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In order to reduce complexity and to focus on user-friendliness, the GEA IO control generation will now be available for every separator and decanter. Initially launched in 2014 for decanters, GEA IO has been revised and improved to use it for all GEA centrifuges – for every kind of application. The development of GEA IO has been focusing on user’s needs, aiming to keep the control as simple and user-friendly as possible. Consistently reduced to the essentials, operators are quickly…

September 5, 2017

NewAge® Industries Achieves Landfill-Free Status

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NewAge Industries is proud to announce that it is now a zero-waste organization. All of the tubing manufacturer’s waste is reused, recycled or disposed of by combustion at a local EfW (Energy from Waste) facility. “This has been a goal of ours as part of our sustainability program,†noted Ken Baker, CEO. “We went solar in 2011. Plant investments followed in the form of new windows, energy efficient lighting, building insulation and high efficiency motors and capacitors. Going landfill free…

August 30, 2017

Single-Use Powder Containment Solution

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This webcast features: David Howes, ILC Dover Learn about modern single-use powder containment best practices and how to reduce cross contamination and airborne particulates.   You will gain insight on how you can increase safety and speed when handling powders.  In the study, we will discuss the ease of fill along with dispensing times and product loss. ILC Dover’s EZBiopac® shows a 71% decrease in filling times when measured against an industry standard 2D bag. Due to the non-static film we…

August 30, 2017

Proper Task Performance in GMP BioManufacturing: Human Error Reductions

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This webcast features: Tony Fultz, Director of Upstream Manufacturing at Fujifilm Diosynth Biotechnologies. Human error reduction should be a top priority of every organization. Our company, clients, and most importantly, our patients are heavily dependent on right first time execution. Human error is, and will likely always be, the highest contributor to deviations and batch failures. Fujifilm Diosynth Biotechnology (FDB) is aggressively seeking to reduce human error. Using his experience in the nuclear industry, Tony Fultz shares a method implemented…

August 28, 2017

Ajinomoto Althea, Inc. Announces New Aseptic Fill Finish Line

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Ajinomoto Althea, Inc., a leading service provider of biopharmaceutical contract development and manufacturing drug programs, announces the installation and launch of a new high-performance sterile vial filling line. The new Optima VFVM 7000 aseptic fill finish line further strengthens Althea’s drug product manufacturing capabilities and supports a broad range of drug substance APIs compatible with both peristaltic and rotary piston pump filling systems. This new filling line expands Althea’s current capabilities by enabling larger batch sizes and a broader range…

August 25, 2017

Modular, Single-Use Facilities Increase Biomanufacturing Flexibility

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The pipelines of biopharmaceutical companies are becoming increasingly diverse while improvements in cell lines are leading to more productive bioprocesses. These factors are driving new capacity demands for bio-pharmaceutical companies and their CDMO partners. It is becoming increasingly important, therefore, that companies implement innovative, highly efficient, flexible facilities that are capable of meeting these challenging capacity demands. Login to view full PDF version of poster.

August 9, 2017

ANGUS Life Sciences Expands U.S. Biotechnology Commercial Team

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ANGUS Life Sciences, a business of ANGUS Chemical Company, and the world’s only fully integrated manufacturer of TRIS AMINOâ„¢ tromethamine buffers, has announced the addition of five regional account managers to cover the U.S. biotechnology and pharmaceutical markets. The new team bring decades of combined industry experience and are playing an essential role in further developing relationships with leading biotechnology and pharmaceutical manufacturers. “The expansion of our Life Sciences team reflects our dedication to providing customers with the highest-quality production…

August 9, 2017