CDMO AGC Bio has picked up a second site in Colorado, buying a cell and gene therapy facility in Longmont from Novartis. The 622,000 square-foot facility in Longmont – north of Denver, Colorado – will become part of AGC Biologics’ ever-growing manufacturing footprint, and will go hand-in-hand with its cell and gene therapy site in Milan, Italy, added through the €240 million ($284 million) acquisition of Molmed last year. “The Longmont facility fits perfectly into AGC’s long-term growth and expansion…
Author Archives: Dan Stanton
Cytiva doubles liquid cell culture media capacity with Intermountain bolt-on
The latest acquisition by Cytiva sees it add Intermountain Life Sciences, gaining a buffer and cell culture media manufacturing site in Utah. Terms of the deal have not been disclosed, but Danaher Corporation subsidiary Cytiva has added a 25,000+ square-foot facility in Salt Lake City, Utah. The site can produce 60,000 L/day of Water for Injection (WFI) and formulation lot sizes to 14,000 L, and will significantly expand Cytiva’s bioprocessing offering, said Olivier Loeillot, VP of Cytiva. “This acquisition is…
Amgen to build $365m Ohio plant to support drug packaging
The facility in New Albany, Ohio will support assembly and packaging for a range of Amgen’s medicines, the firm says. The $365 million investment will see Amgen construct a 270,000 square-foot facility in New Albany, creating around 400 jobs ranging from technicians, engineers, quality assurance, quality control, administrative and management positions. “The facility will assemble, label and package vials and syringes for a wide variety of Amgen medicines,†Amgen spokeswoman Megan Fox told BioProcess Insider. “This new final product advanced…
Fujifilm pumps another $850m into its CDMO business
Fujifilm Diosynth Biotechnologies (FDB) will double cell culture production for recombinant vaccines in the US and increase gene therapy production in the UK ten-fold as part of its latest investment plans. The Â¥90 billion ($850 million) expansion will increase capacity across a range of modalities on both sides of the Atlantic. As well as doubling cell culture production for recombinant vaccines in the US, the firm will grow capacity at its Teeside, UK site to increase gene therapy production ten-fold,…
Sanofi doubles down on mRNA vaccines with $475m annual booster shot
‘The mRNA story is just beginning’ says Sanofi as it builds on its partnership with Translate Bio by launching dedicated vaccine R&D centers in Massachusetts and France. The French pharma giant announced plans today to invest €400 million ($475 million) annually into what it describes as its ‘mRNA Center of Excellence’ to accelerate R&D of next-generation vaccines. The ‘Center’ will in fact be spread across two of Sanofi’s locations, Cambridge (Boston) in Massachusetts and in Marcy L’Etoile (near Lyon), France,…
$250m CAR-T startup ‘validates’ Intellia’s allogeneic and CRISPR platforms
Intellia Therapeutics, Blackstone, and Cellex have launched a CAR-T biotech aimed at developing chimeric antigen receptor (CAR) T-cell therapies. The new company will combine Intellia’s allogeneic cell platform and CRISPR cell engineering with Cellex subsidiary GEMoaB’s switchable universal CAR-T platforms – UniCAR and RevCAR – to develop a range of therapies against various cancers, including solid tumors. Blackstone Life Sciences has invested $250 million in the new venture, and the three companies – Blackstone, Intellia, and Cellex – will each…
Repligen buys French filtration firm Polymem
Repligen Corporation has continued its M&A spree with the acquisition of hollow fiber technology firm Polymem. The deal, once complete, will see Repligen add Toulouse, France based ultra and microfiltration tech firm Polymem to its bioprocess portfolio. Polymem was established in 1997 by two engineers specializing in hollow fiber membrane manufacturing and has built itself up into a firm servicing numerous industries, including the biomanufacturing sector. “The acquisition significantly expands our hollow fiber membrane and module production capabilities and adds…
ViiV to get under the skin of HIV through $40m Halozyme deal
Halozyme’s ENHANZE drug delivery technology gives ViiV Healthcare more “shots on goal†to develop ultra-long acting drugs against HIV, the firm says. ViiV Healthcare, owned by GlaxoSmithKline (GSK) with investments from Pfizer and Shionogi, paid Halozyme Therapeutics $40 million upfront this week to use the latter’s ENHANZE drug delivery technology across several candidates targeting HIV. Halozyme could receive up to $175 million in development and commercial milestones per target. “The four specific HIV medicine targets will expand opportunities for development…
Novartis and Allergopharma sites get EU OK to make Pfizer COVID vaccine
The European Medicines Agency (EMA) has approved sites in Switzerland and Germany for the fill and finish of Pfizer/BioNTech’s COVID-19 vaccine Comirnaty. At the beginning of the year, Pfizer entered into a deal with fellow Big Pharma firm Novartis for the supply of its COVID-19 vaccine Comirnaty, codeveloped with German firm BioNTech. Novartis is providing aseptic manufacturing services from its Stein, Switzerland, facility under a contract manufacturing agreement that sees the company take bulk mRNA active ingredient from BioNTech and…
Vectorized antibody startup VectorY to establish Dutch plant
VectorY Therapeutics will use a portion of its recent €31 ($37) million seed financing to construct a plant in The Netherlands to support its vectorized antibody gene therapy candidates. The biotech, which launched in October 2020 at the Amsterdam Science Park in The Netherlands, secured €31 million through the funding round led by a syndicate that included Forbion, BGV, and Eli Lilly and Company. The money will be used to both establish preclinical proof of the firm’s concept for vectorized…