Boehringer Ingelheim BioXcellenceâ„¢ is your dedicated biopharmaceutical contract manufacturer. As a leading biopharmaceutical contract manufacturer with more than 35 years of experience, it has brought 22 biopharmaceutical products to market. Boehringer Ingelheim BioXcellenceâ„¢ offers tailor-made contract development and manufacturing services to the biopharmaceutical industry, providing the entire production technology chain from DNA to fill and finish under one roof at its facilities in Biberach (Germany), Vienna (Austria), Fremont (USA), and Shanghai (China). Boehringer Ingelheim BioXcellenceâ„¢ can secure product supply throughout the entire product life cycle transferring customer projects at any stage, delivering to almost any scale. Boehringer Ingelheim BioXcellenceâ„¢ makes outsourcing easy.

Boehringer Ingelheim BioXcellenceâ„¢ Services

At our cell culture sites in Biberach (Germany) and Fremont (USA), we have a total capacity of more than 200,000 L, with flexible scales for clinical and commercial supply of between 400 L and 12,000 L. At our microbial site in Vienna (Austria), we have more than 12,000 L with flexible scales for clinical and commercial supply from 200 L to 4,500 L. At our new cell culture site in Shanghai (China), we will have a flexible, fully disposable GMP facility for clinical and early commercial supply from 100 L to multiple 1,000 L, respectively.

We offer the following:

• Genetic engineering
• Cell line and strain development
• Up- and downstream processing
• Fast and tailored project transfers
• Large-scale GMP facilities licensed by the EMA, the FDA, and the MHLW
• Formulation and pharmaceutical process development
• Fill and finish (including innovative application devices)
• Quality control and assurance.

Boehringer Ingelheim BioXcellenceâ„¢ Experience

Boehringer Ingelheim BioXcellenceâ„¢ offers reliable world-class biopharmaceuticals contract manufacturing to the pharmaceutical and biotechnology industries. We offer a complete range of services, from cell line and strain development through process development and large-scale manufacturing to fill and finish. Our extensive portfolio of capabilities and technologies includes the production of antibodies, recombinant proteins, non-antibody scaffolds, Fab fragments, as well as pDNA from both mammalian cell culture and microbial fermentation systems.

Opportunities for Boehringer Ingelheim BioXcellenceâ„¢ Partners

• From DNA to drug product in one seamless, integrated process
• Small- and large-scale cGMP production in multiproduct facilities that are approved by the major authorities
• The confidence that you are working with a contract manufacturer that has helped bring 22 biopharmaceuticals to the market and with an outstanding track record of >150 projects successfully optimized and transferred
• Transparent processes and first-class project management, allowing you to step in at any stage of development. •

Pauline Bronzel, Boehringer Ingelheim BioXcellenceâ„¢ marketing, Binger Strasse 173, 55216 Ingelheim, Germany; 49-6132 77; BioXcellence@boehringer-ingelheim.com; www.bioxcellence.com.