This webcast features: Sibylle Heidelberger, Technical Marketing Manager for Biologics, SCIEX.
Biotherapeutic peptide mapping LC-MS acquisition methods can make it difficult to routinely identify low-level modifications, such as deamidation and oxidation.
This webinar discusses how the use of generic SWATH® Acquisition method on the benchtop X500B QTOF System and BioPharmaView™ Software allows you to confirm the identity of low-level attributes with fast and accurate batch analysis and processing.
She also presents how the use of this unbiased data-independent SWATH® Acquisition method will effectively create a high-quality digital record of a biologic sample for consistent and sensitive detection of low abundance critical quality attributes (CQAs).
- How to utilize a simple, generic SWATH® Acquisition method to collect high-quality MS/MS on every detectable peptide in a biologic sample preparation, for confident identification of low level attributes
- How to increase the throughput of routine peptide mapping analyses without compromising data quality and sensitivity
- How to obtain an unbiased and complete digital record of a biologic sample that can be interrogated or compared with data from other project sites, without the need for sample reanalysis