Amgen thanks BMS-Celgene merger in creating China opportunity

The opportunistic nature of its partnership with BeiGene threw Amgen into the ever-increasingly attractive China market, management said at JP Morgan.

At the JP Morgan Healthcare Conference in San Francisco this week, Amgen reflected on its 2019 M&A activity and counted itself as a beneficiary of rival Big Biopharma firm Bristol-Myers Squibb’s (BMS)  Celgene acquisition for $74 billion (€66 billion).

From a product perspective, regulatory divestiture demands led Amgen to pick up the global rights to psoriasis drug Otezla (apremilast) for $13.4 billion. But from a global market perspective, CFO Peter Griffith recognized the BMS-Celgene deal as kickstarting Amgen’s strategy for the burgeoning China market.

Image: iStock/MasterSergeant

In June last year, Celgene paid BeiGene $150 million to annul a development and commercialization partnership inked in 2017 to fulfill regulatory demands ahead of the BMS merger. Six months later, Amgen took a $2.7 billion stake – roughly 20% of the company – in the Chinese drugmaker, inking a development and commercialization deal in the region.

“When Celgene announced its original collaboration with BeiGene, that was a watershed moment in the industry, a watershed moment because the deal was focused on innovation arising from China,†Griffith told the audience in San Francisco.

“We were very fortunate that as a result of the Bristol Celgene transaction, BeiGene needed to find another collaborator and we were able to step into what we hope will be a very productive partnership.â€

Amgen managed to tap into the China market on its own, launching cardiovascular disease monoclonal antibody Repatha (evolocumab) in the region last year. But Griffith told investors there is a huge amount of innovation coming out of the region, supported by “a tremendous amount of cash that’s being invested in biotechnology,†which will make China itself a future hub of drug discovery and development.

“So all-in-all it’s already the second largest market, it’s growing rapidly,†he said. “If you’re looking at 10, 15, 20-year horizon, you can’t be a world leading biopharmaceutical company without a substantial sophisticated infrastructure in that country.â€