Monday, March 7, 2022 Daily Archives

Increasing Productivity of IVT Reaction Using At-Line Monitoring by HPLC Chromatography

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This webcast features: Rok Sekirnik, PhD, Head of Process Development mRNA/pDNA, BIA Separations, now a Sartorius company. In Vitro Transcription (IVT) reactions are normally performed as batch processes. Considering their catalytic basis, it is possible to extend reaction times and yields by continuous addition of consumed reagents to the reaction mixture. However, fed-batch strategies reported to date have only managed to achieve a 40 – 100% increase in the production of mRNA. One of the main limitations of development has…

March 7, 2022

Biovian to make AAVs for ANLBIO Alzheimer’s gene therapy candidate

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CDMO Biovian Oy says it has the capacity to support viral vector needs through trials and beyond for ANLBIO from its Turku, Finland facilities. The deal sees biotech ANLBIO contract Biovian to support upcoming trials of its Alzheimer’s disease gene therapy candidate ANL-101. Financials have not been disclosed, but the Finnish contract development and manufacturing organization (CDMO) will supply GMP Cell Bank manufacturing, process and analytical development, and validation of product-specific analytical methods from its site in Turku. “This is…

March 7, 2022

VR training can help meet industry demand, says CGT Catapult

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CGT Catapult has started to include virtual reality (VR) training across the entirety of its skills development programs to meet demands of the industry.  Workforce development opportunities are a focal point in the pharma space as there is a general consensus among professionals that the amount of talent coming through the ranks does not match the huge investment in capacity being seen across the life sciences industry.   With many roles requiring highly skilled workers, training programs are being altered and updated to…

March 7, 2022