Thursday, December 9, 2021 Daily Archives

Protecting Protein Stability with a Novel Grade of Sucrose

by

Ensuring the chemical and physical stability of the therapeutic protein is critical to the safety and efficacy of biopharmaceuticals and presents one of the major challenges in formulation. A number of excipients, including sugars, can be used to solve this problem. Sugars are stabilizers that maintain conformational stability by preferential exclusion and function as cryo- and lyoprotectors in lyophilized formulations. Given these properties, it is not surprising that sucrose is one of the most widely used stabilizers in marketed drug…

December 9, 2021

GenScript opens plasmid facility in China

by

GenScript has opened its plasmid manufacturing plant in Zhenjiang, China, which will provide customers with a one-stop service, says firm. According to GenScript ProBio, its second plasmid facility is the largest one in China with a total floor space of 6,400 square-meter, which will support development of cell and gene therapies and messenger RNA (mRNA) drugs. Additionally, the firm claim the plant establishes its position in the contract development manufacturing organization (CDMO) field – providing more than double plasmid production…

December 9, 2021

‘Incredible demand’ for talent leaving gaps throughout bio-outsourcing space

by

Pharma recruitment firm Lead Candidate says a perfect storm of factors has contributed to a shortage of professionals across key functions, and the pandemic has only made recruiting more difficult. Business across the pharma and bio-outsourcing space is robust, whether at third-party manufacturing companies, contract research organizations (CROs), or pharma services firms. However, such a vigorous environment means the need for skilled staff has never been higher, creating something of a bottleneck going forward. Life sciences talent sourcing firm Lead…

December 9, 2021