Tuesday, August 24, 2021 Daily Archives

Design and Performance of a New Single-Use pH Sensor with Long Shelf Life and High Stability

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Single-use biopharmaceutical manufacturing systems require gamma-sterilizable, highly stable, accurate, and simple-to-use single-use pH sensors with a long shelf life. Herein we report the design and performance of a single-use pH sensor technology optimized for single-use bag applications such as those found in bioreactor and mixing applications. This technology is the basis of Emerson’s Rosemount 550pH Single-Use Sensor. The sensor is compatible with gamma irradiation and can be attached to a single-use bioreactor bag via industry accepted ports. With the incorporation…

August 24, 2021

Clamp-On Flow Meters for Process Monitoring

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Process monitoring entails systematic recording or measurement of an operation or process by means of technical aids. Repeated, regular execution is a central element of that activity. Statistical process control and management help to optimize and stabilize processes. They also ensure appropriate monitoring of threshold values. Ultrasound-based clamp-on flow meters are ideal measuring methods for that purpose because they enable data collection without requiring operators or equipment to intervene in a process. Noncontact flow sensors also combine high precision with…

August 24, 2021

Lonza bulks up China offering with drug product plant

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Lonza says the investment will establish drug product manufacturing capabilities at its facility in Guangzhou, China. Swiss contract development manufacturing organization (CDMO) will install an aseptic fill-finish manufacturing line at its 17,000 square-foot mammalian facility, which began operations in Q2 2021. “With this drug product manufacturing line completed, Lonza represents a complete solution provider to the China market with a special focus on pre-clinical and clinical projects,†said Jeff Li, VP of Commercial Development, Lonza. “This drug product line and…

August 24, 2021

WuXi’s ongoing capacity drive ups planned MA investment to $300m

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WuXi Biologics is expanding bioreactor capacity at its site in Worcester, Massachusetts from 6,000 L to 24,000 L to support demand for biomanufacturing onshoring. Plans for a first US facility were drawn up by China-headquartered contract development and manufacturing organization (CDMO) WuXi Biologics in 2018, with construction beginning in Worcester two years later. But after winning planning approval from the local council last week, WuXi Biologics will expand the site, quadrupling bioreactor single-use capacity through an additional $235 million of…

August 24, 2021