Strong demand for large-scale single-use systems has driven Thermo Fisher to launch bioreactors with capacities beyond the standard limits. Single-use bioreactors have become a staple in the bioprocess industry, both for clinical and commercial batches. Traditionally, these have been restricted in size due to pressure challenges from the increased weight of the liquid medium in larger volume bags with 2,000 L being the upper limit. Thus, if biomanufacturers require larger volumes, they generally would run several systems in unison or…