Thursday, March 15, 2018 Daily Archives

Sartorius Stedim Biotech Launches New ambr® 250 High Throughput Bioreactor System for Perfusion Culture

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Sartorius Stedim Biotech (SSB) announced the launch of the ambr® 250 high throughput (ht) perfusion bioreactor. This is a new automated parallel bioreactor system specially designed for rapid cell culture perfusion process development to optimize production of therapeutic antibodies. The ambr 250ht perfusion system has been developed in collaboration with major biopharma companies. It combines 12 or 24 single-use perfusion mini bioreactors (100-250 mL working volume) with associated single-use perfusion components, all controlled by one automated workstation. The combination of…

March 15, 2018

eBook: Viral Vaccine Production — Cultivation of Vero Cells in Packed-Bed Bioreactors

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Vero cells are anchorage-dependent cells that are used widely as a platform for viral vaccine production (1). In stirred-tank bioreactors, they are grown ordinarily on microcarriers. Fibra-Cel disks are an alternative attachment matrix because they provide a three-dimensional environment that protects cells from damaging shear forces. However, such disks have not been tested for the cultivation of Vero cells. We tested whether benchtop single-use and glass bioreactors with a packed bed made of Fibra-Cel disks would be suitable for cultivation…

March 15, 2018