Thursday, April 20, 2017 Daily Archives

Synergizing Transient and Stable Protein Expression for Accelerated Biotherapeutic Development

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This webcast features: Krista Steger, PhD, Scientist, MaxCyte Transitioning early stage discovery efforts with later stage development activities is critical for moving biological therapies into the clinic in an efficient and timely manner. MaxCyte’s scalable Flow Electroporation™ Technology allows gram-scale transient expression of antibodies and other proteins in cell types that are relevant to biomanufacturing. At the same time, the high levels of efficiency and viability provided by MaxCyte transfection, can shorten timelines and reduce labor involved in generating clonal cell…

April 20, 2017

Distek, Inc. Releases Model 2500 Select Bathless Dissolution Tester

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Distek, Inc., has released the Model 2500 Select – Bathless Dissolution Tester. The patented bathless technology eliminates the water bath and all associated maintenance while heater jackets raise media temperature from ambient to 37°C in less than 15 minutes. Wireless in-shaft temperature sensors continuously monitor and display the in-vessel temperature for each vessel. A brilliant touch screen and unparalleled command of the instrument with electronic tracking of serialized stirring elements, qualification status and due dates and extensive reporting and method…

April 20, 2017

Enzo Life Sciences Introduces Innovative Ultra-Sensitive Multiplex IHC Kit

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Enzo Life Sciences has released a new immunohistochemistry product, MULTIVIEW® PLUS (mouse-HRP/rabbit-AP) IHC Kit (Brown/Green). This non-biotin nanopolymer detection system contains reagents and materials that detect and localize antigens in formalin-fixed paraffin-embedded tissues. The MULTIVIEW PLUS IHC kit optimizes IHC processes by including the entire workflow, from antigen retrieval to visualization. The MULTIVIEW PLUS system can detect multiple antigens on a single tissue sample, while eliminating the traditional two-step method using biotin/avidin conjugates. The high sensitivity, low background reagents are…

April 20, 2017

Multi-Gram Scale Antibody Production Using CHO Cell Transient Gene Expression (TGE) via Flow Electroporationâ„¢ Technology

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Despite advances in transfection methods and culture optimization, many CHO-based TGE systems produce insufficient antibody titers (low mg/L level) for full use within biotherapeutic development pipelines. The high productivity of MaxCyte-driven transient gene expression allows for its use in early phase candidate identification as well as for generating the gram-level antibody quantities needed for later stage pharmacology, stability and manufacturing studies. In this white paper, data are presented demonstrating the reproducibility, scalability and antibody production capabilities of MaxCyte Flow Electroporationâ„¢…

April 20, 2017